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General Information
Symbol
Dmel\nacGfr-1
Species
D. melanogaster
Name
FlyBase ID
FBal0191461
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Gfr1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Δ2-3 activity on GfrEY01553 results in an approximate 0.8kb deletion of the 5' end of Gfr, including a putative initiation codon.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Gfr1 homozygotes, Gfr1/Gfr2 and Gfr1/Df(3R)Exel6147 mutants exhibit a wing-notch phenotype at 18oC but not 25oC. Gfr1 homozygotes exhibit a small terminal delta in veins III and IV of the adult wing at 25oC.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
NOT suppressed by
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

The Gfr1 mutant wing-notch phenotype phenotype is rescued through expression of Hsap\GfrScer\UAS.cIa or Hsap\GfrScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI.

The Gfr1 mutant wing-notch phenotype is rescued through expression of Hsap\GfrScer\UAS.cIa or Hsap\GfrScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI.

Complementation and Rescue Data
Comments

The Gfr1 mutant phenotype is rescued through expression of GfrScer\UAS.cIa or GfrScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI. Expression of Hsap\GfrR147C.Scer\UAS, under the control of Scer\GAL4Act5C.PI does not suppress the wing-notch phenotype observed in Gfr1 mutants.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)