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General Information
Symbol
Dmel\ykiΔ.w
Species
D. melanogaster
Name
FlyBase ID
FBal0191484
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The entire yki gene has been replaced by a w+mW.hs marker.

Insertion components
TI{TI}ykiΔ.w
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In comparison to wild-type clones, ykiΔ.w mutant clones are almost completely eliminated from wing disc tissue.

ykiΔ.w null mutants are homozygous lethal and die as late embryos and early first instar larvae. Using Scer\FLP1ey.PN to selectively induce ykiΔ.w in over 90% of the eye disc cells results in eyes that are markedly reduced in size when compared to wild-type animals. ykiΔ.w-mutant clones generated at 40 hours after egg deposition are hardly observed in third instar wing discs, with rare clones recovered containing only a few cells. ykiΔ.w mutant clones generated at a similar stage are more frequently recovered in the eye discs but contain much fewer cells than the wild-type twin spots. ykiΔ.w mutant clones do not perturb early retina differentiation.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of thScer\UAS.cHa, under the control of Scer\GAL4tub, in ykiΔ.w mutant clones generated in the wing disc, rescues the lethality of these clones but results in clones that are smaller than those generated in wild-type controls.

Expression of banEP3622, under the control of Scer\GAL4tub, in ykiΔ.w mutant clones generated in the wing disc rescues the lethality of these clones, resulting in clones that are larger than those generated in wild-type controls.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of ykiScer\FRT.αTub84B completely rescues ykiΔ.w animals to viable and phenotypically normal adult flies.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ykiΔ.w
Name Synonyms
Secondary FlyBase IDs
    References (2)