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General Information
Symbol
Dmel\cv-cUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Denholm
FlyBase ID
FBal0191512
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Cv-c
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of full-length cv-c.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of cv-cScer\UAS.cDa under the control of Scer\GAL4GMR23E10 in cv-cC524/cv-cMB03717 heterozygous adults does not result in significant changes in the sensitivity to electric shocks, as assessed by maximal motor velocities, or in the preference score to the 4-methylcyclohexanol odorant in ad libitum sleep conditions, as compared to controls.

Expression of cv-cScer\UAS.cDa in motoneurons under the control of Scer\GAL4OK6 fails to rescue the abnormal quantal content (QC) phenotype of cv-c1/+ larvae.

Expression of cv-cScer\UAS.cDa in muscle under the control of Scer\GAL4G14 rescues the abnormal quantal content (QC) phenotype of cv-c1/+ larvae.

Expression of cv-cScer\UAS.cDa under the control of Scer\GAL4ems.HRE results in a failure of invagination of the most distal cells of the posterior spiracular chamber.

Malpighian tubules that express cv-cScer\UAS.cDa under the control of Scer\GAL4ct.CtB are significantly shorter in length and fatter around their circumference than wild-type tubules. The length of the tip cell is increased; the tip cell stalk is ~7μ in wild-type tubules, but can be up to 50μ in Scer\GAL4ct.CtB>cv-cScer\UAS.cDa tubules.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The increased quantal content (QC) measured at the neuromuscular junction of DysE6/+ mutants is not reduced as a result of expression of cv-cScer\UAS.cDa under the control of Scer\GAL4G14.

Expression of cv-cScer\UAS.cDa, under the control of Scer\GAL469B partially suppresses the Egfrf2 mutant invagination phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The expression of cv-cScer\UAS.cDa under the control of Scer\GAL4cv-c-C5 (the intrinsic Gal4 driver of cv-cC5) or of Scer\GAL4104Y fully rescues the decreased mean sleep time exhibited by cv-cC5/cv-cMB03717 or cv-cC524/cv-cMB03717 transheterozygous adults, respectively, reared under 12h light:12h dark cycles.

The expression of cv-cScer\UAS.cDa under the control of Scer\GAL4GMR23E10 rescues the decreased mean sleep time, the lower sleep recovery after overnight sleep deprivation and the short-term olfactory memory decrease under ad libitum sleep conditions exhibited by cv-cC524/cv-cMB03717; expression in these mutants does not significantly alter the sensitivity to electric shocks, as assessed by maximal motor velocities, nor the preference score to the 4-methylcyclohexanol odorant in ad libitum sleep conditions.

Expression of cv-cScer\UAS.cDa in motoneurons under the control of Scer\GAL4OK6 fails to rescue the abnormal quantal content (QC) phenotype of cv-c1/+ larvae.

Expression of cv-cScer\UAS.cDa in muscle under the control of Scer\GAL4G14 rescues the abnormal quantal content (QC) phenotype of cv-c1/+ larvae.

Expression of cv-cScer\UAS.cDa, under the control of Scer\GAL4ct.CtB, partially rescues the Malpighian tubule phenotype of cv-cM62 embryos.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
cv-cScer\UAS.cDa
cv-cUAS.cDa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Denholm
Secondary FlyBase IDs
    References (5)