FB2025_04 , released October 2, 2025
Allele: Dmel\cbtUAS.cMa
Open Close
General Information
Symbol
Dmel\cbtUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Munoz-Descalzo
FlyBase ID
FBal0191622
Feature type
allele
Associated gene
Dmel\cbt
Associated Insertion(s)
Carried in Construct
P{UAS-cbt.M}
Also Known As
UAS-cbt
Key Links
Transgenic product class
cDNA
(Munoz-Descalzo et al., 2005)
wild_type
(Munoz-Descalzo et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Munoz-Descalzo et al., 2005)
wild_type
(Munoz-Descalzo et al., 2005)
Mutagen
in vitro construct
(Munoz-Descalzo et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-cbt.M}
Cytology
Description

UASt sequences drive expression of cbt (sequence corresponds to clone SD06353).

(Munoz-Descalzo et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cbt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of cbtUAS.cMa under the control of Scer\GAL4GMR.PU induces ectopic mitosis in the pupal eye. Clonal expression under the control of Scer\GAL4Tub.PU also induces ectopic mitosis in the pupal eye, resulting in clones with increased number of cells, and in the pupal wing.

      The expression of cbtUAS.cMa under the control of Scer\GAL4en.PU induces increased mitosis in the third instar larval wing disc posterior compartment and ectopic mitosis in the pupal wing disc posterior compartment.

      Adulthood-only expression of cbtUAS.cMa under the control of Scer\GAL4esg.PU leads to increased mitoses in the gut; clonal expression leads to a virtually complete gut renewal by day 6 of expression.

      (Zhang et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      NOT suppressed by
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Tub.PU/cbtUAS.cMa is a non-suppressor of wing disc | somatic clone | third instar larval stage phenotype of E2f107172

      (Zhang et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      cbtScer\UAS.cMa
      cbtUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Munoz-Descalzo
      (Munoz-Descalzo et al., 2005)
      Secondary FlyBase IDs
        References (4)