Allele Dmel\Dcp-1^Scer\UAS.cPa

General Information
Symbol	Dmel\Dcp-1^Scer\UAS.cPa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Page	FlyBase ID	FBal0191704
Feature type	allele	Associated gene	Dmel\Dcp-1

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Page et al., 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\UAS regulatory sequences drive expression of Dcp-1. The Dcp-1 sequence corresponds to a NotI/XhoI digestion of LD10653. (Page et al., 2005)
Carried in construct	P{UAS-Dcp-1.P} (Mendes et al., 2009, Page et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	increased cell death, with Scer\GAL4^ninaE.PT (Mendes et al., 2009)
Phenotype Manifest In
	outer photoreceptor cell, with Scer\GAL4^ninaE.PT (Mendes et al., 2009)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Dcp-1^Scer\UAS.cPa, Scer\GAL4^ninaE.PT has increased cell death phenotype, suppressible by ninaA[+]/ninaA^E110V, Scer\GAL4^ninaE.PT (Mendes et al., 2009)
NOT Suppressor of
Statement Reference Scer\GAL4^unspecified/Dcp-1^Scer\UAS.cPa is a non-suppressor of mitotic cell cycle defective phenotype of pita⁰²¹²¹ (Page et al., 2005)
Phenotype Manifest In
Suppressed by
Statement Reference Dcp-1^Scer\UAS.cPa, Scer\GAL4^ninaE.PT has outer photoreceptor cell phenotype, suppressible by ninaA[+]/ninaA^E110V, Scer\GAL4^ninaE.PT (Mendes et al., 2009)
Additional Comments
Genetic Interactions
Statement Reference Loss of one genomic copy of ninaA, using the amorphic allele ninaA[E110V], protects the outer photoreceptor cells from Dcp-1[Scer\UAS.cPa]-induced apoptosis. (Mendes et al., 2009) Dcp-1^Scer\UAS.cPa fails to rescue the cell cycle phenotype of pita⁰²¹²¹ mutants. (Page et al., 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Dcp-1^Scer\UAS.cPa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Page (Page et al., 2005)
Secondary FlyBase IDs

References ( 2 )
Research paper	Mendes et al., 2009, EMBO J. 28(9): 1296--1307 ER stress protects from retinal degeneration. [FBrf0207956] Page et al., 2005, EMBO J. 24(24): 4304--4315 Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. [FBrf0190363]

Allele Dmel\Dcp-1Scer\UAS.cPa

Allele Dmel\Dcp-1^Scer\UAS.cPa