DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by Mgat1KK101668, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by Mgat1KK101668, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by IdeKK107536, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by IdeKK107536, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by YL-1KK100166, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by YL-1KK100166, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by RhoGAP68FKK102738, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by RhoGAP68FKK102738, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by DEF8KK101896, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by DEF8KK101896, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by HINT1KK108645, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by HINT1KK108645, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by Mp20GD11396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by Mp20GD11396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by TctpGD11431, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by TctpGD11431, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by Liprin-αKK100116, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by Liprin-αKK100116, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by Rap1dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by Rap1dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by CamKK109037, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by CamKK109037, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, enhanceable by AxnGD1334, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, enhanceable by AxnGD1334, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by mirrDFM3/mirr[+]
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by mirrGD16318, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by ctdsRNA.cGa.UAS/BacA\p35UAS.cUa, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by ctdsRNA.cGa.UAS, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has abnormal size phenotype, enhanceable by Utx[+]/Utx1
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by atodsRNA.UAS.J, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by atoERD.UAS.Tag:MYC, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by bskDN.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, enhanceable by Rbf14/Rbf[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, enhanceable by Rbf14/Rbf[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, non-enhanceable by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, non-enhanceable by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, non-enhanceable by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, non-enhanceable by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, non-enhanceable by trxunspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, non-enhanceable by trxunspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, non-enhanceable by ash1unspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, non-enhanceable by ash1unspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, suppressible | partially by Hsc70-5KK100233, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, suppressible | partially by Hsc70-5KK100233, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, suppressible | partially by Ip259KK101346, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, suppressible | partially by Ip259KK101346, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, suppressible | partially by Arf79FKK101396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, suppressible | partially by Arf79FKK101396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has increased occurrence of cell division | larval stage phenotype, suppressible | partially by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, suppressible | partially by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, suppressible | partially by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, suppressible | partially by Not3ΔCC.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, suppressible | partially by Not3ΔCC.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has abnormal developmental rate phenotype, suppressible | partially by Ilp8MI00727
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by mir-8SC1, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by atoUAS.cJa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by dapUAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible | partially by JraUAS.cEa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by Mmus\Atoh1UAS.cQa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, suppressible by RbfUAS.cDa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by E(z)[+]/E(z)731
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by RbfUAS.cDa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, suppressible by HDAC104556/Rpd3[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by HDAC104556/Rpd3[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, suppressible by Su(var)3-9[+]/Su(var)3-917
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype, suppressible by Su(var)3-9[+]/Su(var)3-917
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype, suppressible by E(z)[+]/E(z)731
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, non-suppressible by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, non-suppressible by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, non-suppressible by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, non-suppressible by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has increased cell death | larval stage phenotype, non-suppressible by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype, non-suppressible by Not3ΔNB.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype, non-suppressible by Not3ΔNB.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible | adult stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia | adult stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has abnormal size | adult stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has increased occurrence of cell division | larval stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has increased cell death | larval stage phenotype
Scer\GAL4ey.PU, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has abnormal developmental rate phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, mir-8SC1, psqGS88A8 has lethal | adult stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has abnormal size phenotype
DlUAS.cDa, Scer\GAL4ey.PH, atoUAS.cJa, lolaGS88A8, psqGS88A8 has increased cell death | third instar larval stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, atoUAS.cJa, bskDN.UAS, lolaGS88A8, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has visible phenotype
DlUAS.cDa, Scer\GAL4Bx-MS1096, lolaGS88A8, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4dpp.blk1, lolaGS88A8, psqGS88A8 has neoplasia phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Mgat1KK101668, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by IdeKK107536, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by YL-1KK100166, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by RhoGAP68FKK102738, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by DEF8KK101896, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by HINT1KK108645, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Mp20GD11396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by TctpGD11431, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Liprin-αKK100116, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Rap1dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by CamKK109037, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by AxnGD1334, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by mirrDFM3/mirr[+]
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by mirrGD16318, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by ctdsRNA.cGa.UAS/BacA\p35UAS.cUa, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by ctdsRNA.cGa.UAS, Scer\GAL4ey.PU
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Utx[+]/Utx1
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by atodsRNA.UAS.J, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by atoERD.UAS.Tag:MYC, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc | third instar larval stage phenotype, enhanceable by atoERD.UAS.Tag:MYC, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by bskDN.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, enhanceable by Rbf14/Rbf[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-enhanceable by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-enhanceable by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-enhanceable by trxunspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-enhanceable by ash1unspecified
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by Hsc70-5KK100233, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by Ip259KK101346, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by Arf79FKK101396, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc phenotype, suppressible | partially by Not3UAS.cVa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by Not3ΔCC.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by mir-8SC1, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye-antennal disc phenotype, suppressible by mir-8SC1, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by atoUAS.cJa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc | third instar larval stage phenotype, suppressible by atoUAS.cJa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by dapUAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible | partially by JraUAS.cEa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by Mmus\Atoh1UAS.cQa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by RbfUAS.cDa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by E(z)[+]/E(z)731
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by HDAC104556/Rpd3[+]
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, suppressible by Su(var)3-9[+]/Su(var)3-917
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-suppressible by Hsc70-3dsRNA.UAS.cUa, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype, non-suppressible by Fen1KK107731, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc phenotype, non-suppressible by Not3ΔNB.UAS, Scer\GAL4ey.PH
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc phenotype
Scer\GAL4ey.PU, psqGS88A8 has eye phenotype
DlUAS.cDa, Scer\GAL4ey.PU, lolaGS88A8, psqGS88A8 has eye phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye-antennal disc phenotype
DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8 has eye disc | third instar larval stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, atoUAS.cJa, lolaGS88A8, psqGS88A8 has eye disc | third instar larval stage phenotype
DlUAS.cDa, Scer\GAL4ey.PH, atoUAS.cJa, bskDN.UAS, lolaGS88A8, psqGS88A8 has eye phenotype
DlUAS.cDa, Scer\GAL4Bx-MS1096, lolaGS88A8, psqGS88A8 has wing disc phenotype
DlUAS.cDa, Scer\GAL4dpp.blk1, lolaGS88A8, psqGS88A8 has wing disc phenotype
Expression of lolaGS88A8. psqGS88A8 and DlUAS.cDa under the control of Scer\GAL4ey.PH leads to eye tumor and metastasis.
The triple expression of DlUAS.cDa, lolaGS88A8 and psqGS88A8 under the control of Scer\GAL4ey.PH induces excessively enlarged eyes and eye tumors and macroscopically visible metastases, as compared to controls. The eye disc shows a disorganized epithelium with defects in the pattern of differentiated cell; there is a decrease in cell divisions (BrdU labelling and pH3 immunostaining) and an increase in apoptosis (Dcp1a immunostaining), as compared to controls.
Co-expression of DlScer\UAS.cDa with lola and psq (using P{GSV1}lolaGS88A8, which is comprised of the lolaGS88A8 and psqGS88A8 alleles) under the control of Scer\GAL4ey.PU induces tumor-like overgrowths in the eye.
The tumor-like overgrowth phenotype seen when DlScer\UAS.cDa is co-expressed P{GSV1}lolaGS88A8 (comprised of the lolaGS88A8 and psqGS88A8) under the control of Scer\GAL4ey.PU is seen with increased frequency when one copy of mirrDFM3 is also present.
The tumor-like overgrowth phenotype seen when DlScer\UAS.cDa is co-expressed P{GSV1}lolaGS88A8 (comprised of the lolaGS88A8 and psqGS88A8) under the control of Scer\GAL4ey.PU is seen with increased frequency upon co-expression of mirrGD16318.
Co-expression of DlScer\UAS.cDa, lolaGS88A8 and psqGS88A8 using Scer\GAL4ey.PH (the so-called 'eyeful' background) results in a delay in pupariation of 26.6 +/- 7.5 hours. This is reverted to a delay of 5.9 +/- 7.1 hours in a Ilp8MI00727 background.
72.5% of flies expressing DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8 under the control of Scer\GAL4ey.PU have eye tumours, with 4.9% having macroscopically visible secondary tumour growths derived from the developing retina. The incidence of primary and secondary tumours in these "eyeful" flies is slightly enhanced by co-expression of ctdsRNA.cGa.Scer\UAS, but is greatly enhanced if the "eyeful" flies also co-express both ctdsRNA.cGa.Scer\UAS and BacA\p35Scer\UAS.cUa.
Flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which causes overexpression of psq and lola) show an eye tumour phenotype. In addition, distant metastasis in the thorax and abdomen is seen in 15% of cases. Co-expression of mir-8SC1 significantly reduces the primary eye tumour size, completely inhibits the incidence of metastases and results in a high incidence of adult lethality.
Scer\GAL4ey.PH-mediated expression of DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8 causes mild overgrowth of the eye (the 'eyeful' phenotype) at 18[o]C.
Scer\GAL4ey.PH-mediated co-expression of DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8 ("eyeful" flies) results in excessively enlarged eyes, and eye tumours occur in 57% of eyes, with 3% of flies showing macroscopically visible metastases derived from the developing retina.
Co-expression of atoScer\UAS.cJa almost completely suppresses the formation of eye tumours seen in 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) flies.
Co-expression of atodsRNA.Scer\UAS.J results in a dramatic increase in tumour and metastases incidence in 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) flies.
Co-expression of atoScer\UAS.T:Rep-en.T:Hsap\MYC results in a dramatic increase in tumour and metastases incidence in 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) flies: differentiated eye tissue is lost in 30% of the eye fields, and tumors are seen in 100% of the remaining eyes. These tumors include large patches of undifferentiated tissue.
Co-expression of atoScer\UAS.cJa in 'eyeful' third instar eye discs (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) results in dramatically increased apoptosis, as measured by decay staining.
Scer\GAL4ey.PH-mediated co-expression of DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8 ("eyeful") third instar eye discs exhibit increased cell proliferation (as measured by phospho-histoneH3) posterior to the second mitotic wave.
Co-expression of atoScer\UAS.cJa reduces ectopic proliferation in "eyeful" (Scer\GAL4ey.PH DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8) third instar eye discs.
Co-expression of atoScer\UAS.T:Rep-en.T:Hsap\MYC increases ectopic proliferation in "eyeful" (Scer\GAL4ey.PH DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8) third instar eye discs.
Co-expression of atoScer\UAS.T:Rep-en.T:Hsap\MYC in a Scer\GAL4ey.PH DlScer\UAS.cDa background leads to the appearance of significant numbers of proliferating cells in the posterior region of third instar eye discs.
"Eyeful" (Scer\GAL4ey.PH DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8) third instar eye discs exhibit disorganization of the epithelium.
Co-expression of atoScer\UAS.cJa restores the size and organization of "eyeful" (Scer\GAL4ey.PH DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8) third instar eye discs.
Co-expression of atoScer\UAS.T:Rep-en.T:Hsap\MYC severely worsens the retinal patterning of "eyeful" (Scer\GAL4ey.PH DlScer\UAS.cDa, psqGS88A8 and lolaGS88A8) third instar eye discs, to the extent that the morphogenetic furrow is difficult to discriminate.
Co-expression of dapScer\UAS.cUa leads to a significant inhibition of the tumor occurrence and a partial reduction in the metastasis seen in 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) flies.
Co-expression of bskDN.Scer\UAS in the 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) background leads to tumors in 61% of eyes and an approximately 7-fold increase in metastasis.
Co-expression of JraScer\UAS.cEa reduces tumor and metastasis incidence in the 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) background.
Co-expression of bskDN.Scer\UAS in a atoScer\UAS.cJa 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) background leads to a suppression of the inhibitory effects of atoScer\UAS.cJa on the 'eyeful' tumor phenotype, restoring tumor formation and enhancing metastasis.
Flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4ey.PH) usually develop tumours in the eyes. Additionally, in approximately 30% of the flies, secondary eye growths are seen throughout the body, with the whole body filling up with eye tissue in some cases. The secondary eye growths have ragged borders, indicating invasion of the mutant tissue into the surrounding normal tissue. Eye discs show massive uncontrolled overgrowth in animals expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4ey.PH). In most of the discs, the epithelial cells have lost their apical-basal polarity and some have a disrupted basement membrane and grow without differentiating. Wing discs of animals expressing DlScer\UAS.cDa under the control of Scer\GAL4dpp.blk1 and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4dpp.blk1) show massive overgrowth and mutant cells are found invading adjacent regions of the disc. Wing discs of animals expressing DlScer\UAS.cDa under the control of Scer\GAL4Bx-MS1096 and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4Bx-MS1096) show massive overgrowth, which initiates in the dorsal region but progressively extends to occupy the whole disc. Flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying psqGS88A8 and lolarev6 have reduced eye tumour size (compared to flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying psqGS88A8 and lolaGS88A8) but show sporadic secondary growth of eye tissue. The eye tumour phenotype of flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4ey.PH) is dominantly suppressed by one of Rpd304556, Su(var)3-917 or E(z)731, is dominantly enhanced by Rbf14, but is not enhanced by trxunspecified or ash1unspecified. The eye tumour phenotype of flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4ey.PH) is suppressed by co-expression of RbfScer\UAS.cDa.
Co-expression of Mmus\Atoh1Scer\UAS.cQa almost completely suppresses the formation of eye tumours seen in 'eyeful' (Scer\GAL4ey.PH, DlScer\UAS.cDa, psqGS88A8, lolaGS88A8) flies.