UASt sequences control expression of Gclm cDNA (EcoRI-XhoI fragment from GH01757) consisting of the entire ORF (857 bp) along with 77 bp of 5'UTR and 202 bp of 3' UTR.
GclmScer\UAS.cOa; Scer\GAL4D42 and GclmScer\UAS.cOa; Scer\GAL4Appl.G1a animals are not significantly longer lived than wild-type.
GclmUAS.cOa, Scer\GAL4ple.PF/Scer\GAL4ple.PF is a suppressor of neuroanatomy defective phenotype of Hsap\SNCAUAS.cTa, Scer\GAL4ple.PF/Scer\GAL4ple.PF
GclmUAS.cOa, Scer\GAL4ple.PF/Scer\GAL4ple.PF is a suppressor of dopaminergic neuron phenotype of Hsap\SNCAUAS.cTa, Scer\GAL4ple.PF/Scer\GAL4ple.PF
Expression of GclmScer\UAS.cOa completely rescues the neuronal loss induced by Hsap\SNCAScer\UAS.cTa expression in 20- and 30-day old flies.