FlyBase Allele Report: Dmel\Ppt1[UAS.cKa]

General Information

Symbol

Dmel\Ppt1^UAS.cKa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct of Korey

FlyBase ID

FBal0193173

Feature type

allele

Associated gene

Dmel\Ppt1

Associated Insertion(s)

Carried in Construct

P{UAS-Ppt1.K}

Also Known As

UAS:Ppt1, UAS-Ppt1

Key Links

Transgenic product class

wild_type

(Korey and MacDonald, 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Korey and MacDonald, 2003)

Mutagen

in vitro construct

(Hickey et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-Ppt1.K}

Cytology

Description

UASt regulatory sequences drive expression of Ppt1.

(Korey and MacDonald, 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Ppt1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^GMR.PF

(Saja et al., 2010)

increased cell death, with Scer\GAL4^GMR.PF

(Korey and MacDonald, 2003)

partially lethal, with Scer\GAL4^elav.PLu

(Hickey et al., 2006)

visible, with Scer\GAL4^GMR.PF

(Buff et al., 2007, Korey and MacDonald, 2003)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Saja et al., 2010, Buff et al., 2007, Korey and MacDonald, 2003)

eye photoreceptor cell, with Scer\GAL4^GMR.PF

(Korey and MacDonald, 2003)

ommatidium, with Scer\GAL4^GMR.PU

(Jones et al., 2014)

rhabdomere of eye photoreceptor cell, with Scer\GAL4^GMR.PF

(Korey and MacDonald, 2003)

Detailed Description

Statement

Reference

Scer\GAL4^GMR.PU-mediated expression of Ppt1^Scer\UAS.cKa leads to a blackened ommatidia phenotype with variable expressivity.

Negative geotaxis is not altered in flies expressing Ppt1^Scer\UAS.cKa via Scer\GAL4^elav.PU.

(Jones et al., 2014)

Overexpression of Ppt1^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF produces a degeneration of the developing adult visual system.

(Saja et al., 2010)

Expression of Ppt1^Scer\UAS.cKa under the control of Scer\GAL4^elav.PLu causes a reduction in viability.

(Hickey et al., 2006)

Expression of Ppt1^Scer\UAS.cKa in the eye under the control of Scer\GAL4^GMR.PF results in adult flies with smaller eyes, disrupted ommatidial number and spacing, and absence of some sensory bristles. Some ommatidia are black in colour. The number of rhabdomeres/ommatidia is reduced in these eyes. Photoreceptor neurons are highly vacuolised with rhabdomeres in various stages of degenerations.

(Korey and MacDonald, 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by foi[+]/foi^j8E8

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by foi[+]/foi^16.33

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by foi[+]/foi^20.71

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by Csk^j1D8/Csk[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by Csk^S017909/Csk[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by zip[+]/zip⁰²⁹⁵⁷

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by zip[+]/zip¹

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by zip²/zip[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by Imp[+]/Imp⁸

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by Imp[+]/Imp^G0072

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by tsg²/tsg[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by tsg[+]/tsg⁴

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by sax^{Q263D.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, enhanceable by shi^UAS.cSa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Mrp4^EP430, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by faf^UAS.cHa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by mys^EP1033, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by mys^UAS.cDa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by msn^EP549, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by msn^UAS.cSa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Naa60^EP3301, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Jarid2^EY00142, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by bchs^EY02503, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by fs(1)N¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Pisd^EY03559, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Frl^EY03931, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by EndoA^EP464, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by EndoA^UAS.cVa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by faf^EY02018, Scer\GAL4^GMR.PF

(Buff et al., 2007)

NOT Enhanced by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, non-enhanceable by Vps28[+]/Vps28^k16503

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by stnB^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by faf^BX4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by mys¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Fas2^EB112

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by m¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by msn¹⁰²

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by sro¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by sax⁵

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by EndoA^Δ4

(Buff et al., 2007)

Suppressed by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, suppressible by Sumo⁰⁴⁴⁹³/smt3[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, suppressible by Sumo^k06307/smt3[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, suppressible by sax^CA.UAS.cUa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, suppressible by gbb^UAS.cKa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by UbcE2H^EP1303, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Usp12-46^EY00249, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Fas2^EP1462, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Fas2^UAS.cHa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by m^EP406, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by kay^EY00283, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by kay^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by sax^EY04377, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by sax^CA.UAS.cUa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by MESR4^EP386, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by fs(1)N^EP1336, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Hsc70-3^EP1507, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by IntS8^EP2090, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Syt1^UAS.cLa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by stnA^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by BacA\p35^GMR.PH

(Korey and MacDonald, 2003)

NOT suppressed by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has abnormal neuroanatomy phenotype, non-suppressible by Vps28[+]/Vps28^k16503

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by EndoA^Δ4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by faf^BX4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by mys¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Fas2^EB112

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by m¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by msn¹⁰²

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by sro¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by sax⁵

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by stnB^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PU has ommatidium phenotype, enhanceable by Cln3^GD2699, Scer\GAL4^GMR.PU

(Jones et al., 2014)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by foi[+]/foi^j8E8

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by foi[+]/foi^16.33

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by foi[+]/foi^20.71

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Csk^j1D8/Csk[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Csk^S017909/Csk[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by zip[+]/zip⁰²⁹⁵⁷

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by zip[+]/zip¹

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by zip²/zip[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Imp[+]/Imp⁸

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Imp[+]/Imp^G0072

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by tsg²/tsg[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by tsg[+]/tsg⁴

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by sax^{Q263D.UAS.Tag:HA}, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by shi^UAS.cSa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Mrp4^EP430, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by faf^UAS.cHa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by mys^EP1033, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by mys^UAS.cDa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by msn^EP549, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by msn^UAS.cSa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by bchs^EY02503, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Naa60^EP3301, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Jarid2^EY00142, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Pisd^EY03559, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by fs(1)N¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Frl^EY03931, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by EndoA^EP464, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by EndoA^UAS.cVa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by faf^EY02018, Scer\GAL4^GMR.PF

(Buff et al., 2007)

NOT Enhanced by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Vps28[+]/Vps28^k16503

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by stnB^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by faf^BX4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by mys¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Fas2^EB112

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by m¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by msn¹⁰²

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by sro¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by sax⁵

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by EndoA^Δ4

(Buff et al., 2007)

Suppressed by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PU has ommatidium phenotype, suppressible | partially by Cisd^GD15791, Scer\GAL4^GMR.PU

(Jones et al., 2014)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PU has ommatidium phenotype, suppressible by Cisd^G6528

(Jones et al., 2014)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PU has ommatidium phenotype, suppressible | partially by Cln3^UAS.cTa, Scer\GAL4^GMR.PU

(Jones et al., 2014)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PU has ommatidium phenotype, suppressible | partially by Cln3^UAS.Venus, Scer\GAL4^GMR.PU

(Jones et al., 2014)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by sax^CA.UAS.cUa, Scer\GAL4^GMR.PF

(Saja et al., 2010, Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Sumo⁰⁴⁴⁹³/smt3[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Sumo^k06307/smt3[+]

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by gbb^UAS.cKa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by UbcE2H^EP1303, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Usp12-46^EY00249, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Fas2^EP1462, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Fas2^UAS.cHa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by m^EP406, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by kay^EY00283, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by kay^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by sax^EY04377, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by MESR4^EP386, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by fs(1)N^EP1336, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Hsc70-3^EP1507, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by IntS8^EP2090, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Syt1^UAS.cLa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by stnA^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by BacA\p35^GMR.PH

(Korey and MacDonald, 2003)

NOT suppressed by

Statement

Reference

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Vps28[+]/Vps28^k16503

(Saja et al., 2010)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by stnB^UAS.cEa, Scer\GAL4^GMR.PF

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by EndoA^Δ4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by faf^BX4

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by mys¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Fas2^EB112

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by m¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by msn¹⁰²

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by sro¹

(Buff et al., 2007)

Ppt1^UAS.cKa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by sax⁵

(Buff et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Negative geotaxis is not altered in flies expressing Ppt1^Scer\UAS.cKa via Scer\GAL4^elav.PU in a Cisd2^G6528 background.

(Jones et al., 2014)

A Vps28^k16503/+ background does not enhance or suppress the eye degeneration phenotype found upon expression of Ppt1^Scer\UAS.cKa under the control of Scer\GAL4^GMR.PF.

A foi^j8E8/+, foi^16.33/+ or foi^20.71/+ background enhances the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

A Csk^j1D8/+ or Csk^S017909/+ background enhances the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

A smt3⁰⁴⁴⁹³/+ or smt3^k06307/+ background suppresses the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

zip⁰²⁹⁵⁷/+, zip¹/+ or zip²/+ backgrounds enhance the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

A Imp⁸/+ or Imp^G0072/+ background enhances the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

A tsg²/+ or tsg⁴/+ background enhances the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

Overexpression of sax^A.Scer\UAS suppresses the adult visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies while overexpression of sax^{Q263D.Scer\UAS.T:Ivir\HA1} enhances it.

Overexression of gbb^Scer\UAS.cKa with Ppt1^Scer\UAS.cKa, both under the control of Scer\GAL4^GMR.PF suppresses the visual system degeneration seen upon Ppt1^Scer\UAS.cKa expression alone.

Co-expression of shi^Scer\UAS.cSa and Ppt1^Scer\UAS.cKa in the developing eye under the control of Scer\GAL4^GMR.PF enhances the eye degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

(Saja et al., 2010)

Xenogenetic Interactions

Statement

Reference

Co-expression of BacA\p35^GMR.PH in animals expressing Ppt1^Scer\UAS.cKa in the eye under the control of Scer\GAL4^GMR.PF significantly reduces the rough eye defects.

(Korey and MacDonald, 2003)

Complementation and Rescue Data

Rescues

Scer\GAL4^elav.PU/Ppt1^UAS.cKa rescues Df(1)446-20

(Aby et al., 2013)

Ppt1^UAS.cKa/Scer\GAL4^elav.PLu rescues Df(1)446-20

(Hickey et al., 2006)

Comments

Expression of Scer\GAL4^elav.PU>Ppt1^Scer\UAS.cKa rescues the spontaneous miniature excitatory junction potential (mini EJP) frequency and locomotory phenotypes observed in Df(1)446-20 mutants.

(Aby et al., 2013)

The accumulation of abnormal storage material seen in the brains of Df(1)446-20 homozygotes is completely suppressed by expression of Ppt1^Scer\UAS.cKa under the control of Scer\GAL4^elav.PLu.

(Hickey et al., 2006)

The rough eye defects in flies expressing Ppt1^Scer\UAS.cKa in the eye under the control of Scer\GAL4^GMR.PF are suppressed in a Df(1)RA2 or Df(1)KA14 mutant background.

(Korey and MacDonald, 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ppt1^Scer\UAS.cKa

Ppt1^UAS.cKa

Name Synonyms

Saccharomyces cerevisiae UAS construct of Korey

Secondary FlyBase IDs

References (7)

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