Allele Dmel\cpa^{Scer\UAS.T:Ivir\HA1}

General Information
Symbol	Dmel\cpa^{Scer\UAS.T:Ivir\HA1}	Species	D. melanogaster
Name		FlyBase ID	FBal0193689
Feature type	allele	Associated gene	Dmel\cpa

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of cpa (corresponds to GH10050), which is tagged with T:Ivir\HA1. (Janody and Treisman, 2006)
Carried in construct	P{UAS-cpa.HA} (Janody and Treisman, 2006, Johnson et al., 2008, Fernández et al., 2011)
Tagged with	T:Ivir\HA1 (Janody and Treisman, 2006)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	eye (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^69E (Janody and Treisman, 2006) eye (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^107E (Janody and Treisman, 2006) eye (with cpa^69E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006) eye (with cpa^107E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006) macrochaeta (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^69E (Janody and Treisman, 2006) macrochaeta (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^107E (Janody and Treisman, 2006) macrochaeta (with cpa^69E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006) macrochaeta (with cpa^107E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006) wing (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^69E (Janody and Treisman, 2006) wing (with cpa^43D), with Scer\GAL4^αTub84B.PL, cpa^107E (Janody and Treisman, 2006) wing (with cpa^69E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006) wing (with cpa^107E), with Scer\GAL4^αTub84B.PL, cpa^43D (Janody and Treisman, 2006)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	cpa^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^αTub84B.PL partially rescues cpa^43D/cpa^107E (Janody and Treisman, 2006) cpa^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^αTub84B.PL partially rescues cpa^69E/cpa^43D (Janody and Treisman, 2006) cpa^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^αTub84B.PL partially rescues cpa^107E (Janody and Treisman, 2006)
Comments	Expression of cpa^{Scer\UAS.T:Ivir\HA1} in the wing disc, under the control of Scer\GAL4^αTub84B.PL, prevents the extrusion of cpa^107E clones from the wing blade primordium. Ubiquitous expression of cpa^{Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^αTub84B.PL rescues the lethality of cpa^43D/cpa^107E and cpa^43D/cpa^69E mutants, although some of the rescued adults exhibit wing, eye or bristle defects. (Janody and Treisman, 2006)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	cpa^{Scer\UAS.T:Ivir\HA1}
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Fernández et al., 2011, Development 138(11): 2337--2346 Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. [FBrf0213674] Johnson et al., 2008, J. Cell Biol. 180(6): 1191--1204 The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. [FBrf0204348] Janody and Treisman, 2006, Development 133(17): 3349--3357 Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epithelium. [FBrf0193788]

Allele Dmel\cpaScer\UAS.T:Ivir\HA1

Allele Dmel\cpa^{Scer\UAS.T:Ivir\HA1}