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General Information
Symbol
Dmel\bchs17
Species
D. melanogaster
Name
FlyBase ID
FBal0193785
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(2L)2299, EP(2)2299
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G5918161A

Amino acid change:

W2640term | bchs-PA

Reported amino acid change:

W2640term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The progenitor P{EP}EP2299 insertion is still present on the chromosome.

Amino acid replacement: W2640term.

Insertion components
P{EP}EP2299
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

bchs17 mutants show no defects in the larval visual system or embryonic central nervous system.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The viability of Rab11ex1/Rab1193Bi is increased when flies are also mutant for either Df(2L)cl7/bchs17, bchs17/bchs12 or bchs17/+.

The microchaeta loss of Rab11ex1/Rab1193Bi flies is significantly suppressed by bchs17/+ and is completely suppressed by Df(2L)cl7/bchs17 or bchs17/bchs12. Further, posterior scutellar bristle length of Rab11ex1/Rab1193Bi flies is restored partially by bchs17/+ and more fully by Df(2L)cl7/bchs17 or bchs17/bchs12.

The bouton density and branching defects of Rab11ex1/Rab1193Bi larval NMJs at muscle 6/7 are significantly suppressed in bchs17/bchs12; Rab11ex1/Rab1193Bi double mutants.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)