FB2025_01 , released February 20, 2025
Allele: Dmel\PtpmegUAS.cWa
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General Information
Symbol
Dmel\PtpmegUAS.cWa
Species
D. melanogaster
Name
FlyBase ID
FBal0193795
Feature type
allele
Associated gene
Dmel\Ptpmeg
Associated Insertion(s)
Carried in Construct
P{UAS-Ptpmeg.W}
Key Links
Transgenic product class
cDNA
(Whited et al., 2007)
wild_type
(Whited et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Whited et al., 2007)
wild_type
(Whited et al., 2007)
Mutagen
in vitro construct
(Whited et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Ptpmeg.W}
Cytology
Description

UAS regulatory sequences drive expression of Ptpmeg (sequence corresponds to cDNA LD22982).

(Whited et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ptpmeg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      PtpmegUAS.cWa/Scer\GAL4elav.PLu partially rescues Ptpmeg1

      (Whited et al., 2007)

      PtpmegUAS.cWa/Scer\GAL4elav.PLu partially rescues Ptpmeg1/Df(3L)ED201

      (Whited et al., 2007)
      Fails to rescue

      PtpmegUAS.cWa/Scer\GAL4EB1 fails to rescue Ptpmeg1

      (Whited et al., 2007)
      Comments

      Expression of PtpmegScer\UAS.cWa under the control of Scer\GAL4elav.PLu fully rescues the alpha lobe defects and partially rescues the beta lobe defects of Ptpmeg1 homozygotes. Scer\GAL4elav.PLu>PtpmegScer\UAS.cWa expression partially rescues the alpha lobe defects of Ptpmeg1/Df(3L)ED201 mutants.

      Expression of PtpmegScer\UAS.cWa under the control of Scer\GAL4elav.PLu rescues the ellipsoid body defects of Ptpmeg1 mutants but expression of this transgene within the ellipsoid body itself, under the control of Scer\GAL4EB1, fails to rescue these defects.

      (Whited et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PtpmegScer\UAS.cWa
      PtpmegUAS.cWa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)