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General Information
Symbol
Dmel\meltUAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Teleman
FlyBase ID
FBal0193838
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-melt
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
Expression of full length melt cDNA is under the control of UASt sequences.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Scer\GAL4en.PU>meltScer\UAS.cTa adult wings are slightly larger than control wings expressing only the driver. Strong overexpression meltScer\UAS.cTa in the developing and adult eye does not noticeably affect eye size or morphology.
The total number of photoreceptors, as well as the number of Rh5-positive and Rh6-positive photoreceptors is normal in the eyes of larvae expressing meltScer\UAS.cTa under the control of Scer\GAL4so-7.GAL4.
Expression of meltScer\UAS.cTa in all photoreceptors, driven by Scer\GAL4GMR.long, causes R8 photoreceptors to adopt a p fate. The dorsal rim area R8 cells are not affected. Expression of meltScer\UAS.cTa, under the control of Scer\GAL4Rh5.PT and Scer\GAL4Rh6.PD in R8 photoreceptor cells, increases the number of cells that adopt an R8 fate and causes ~63% of cells to express both Rh5 and Rh6, which are indicative of both p and y fates. Expression of this transgene in R7 photoreceptor cells, driven by Scer\GAL4Rh3.PP and Scer\GAL4Rh4.PT, does not affect the fate specification of R8 cells.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Eyes that express meltScer\UAS.cTa, under the control of Scer\GAL4GMR.long, in a sev14 background, have a high proportion of pR8 photoreceptors and a small proportion of yR8 receptors.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
The growth defects seen in Df(3L)meltΔ1 homozygous flies are fully rescued by meltScer\UAS.cTa with Scer\GAL4αTub84B.PL or Scer\GAL4ppl.PP, but not with Scer\GAL4Ilp3.PC.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
meltScer\UAS.cTa
meltUAS.cTa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Teleman
Secondary FlyBase IDs
    References (7)