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General Information
Symbol
Dmel\Su(fu)UAS.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0193956
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of full-length Su(fu).
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Escaper adult flies expressing Su(fu)Scer\UAS.cDa under the control of Scer\GAL4da.G32 show anterior duplications in the wing, legs and antennae. In the wing, the domain between the costa and subcosta is enlarged with frequent expanded costa duplications and there are extra, disorganized costa bristles. However, these wings do not show obvious anomalies in the LV3-LV4 region. The first pair of legs belonging to these escapers are shorter and thicker than in wild type and have anterior sex-comb duplications. Legs of the third pair are extremely deformed, with enlarged and fused articles. Adult flies that express Su(fu)Scer\UAS.cDa under the control of Scer\GAL4vg.int2.1 have frequent anomalies in the costa region of the wing, leading to large anterior duplications. Anterior clones expressing Su(fu)Scer\UAS.cDa under the control of Scer\GAL4Act5C.PP in the wing disc lead to disc overgrowth.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Phenotype Manifest In
Enhanced by
Other
Additional Comments
Genetic Interactions
Statement
Reference
In escaper flies that express Su(fu)Scer\UAS.cDa, under the control of Scer\GAL4da.G32, in a fu41 background, the wing phenotype is enhanced compared to flies expressing the transgene in a wild-type background. fu41, Su(fu)Scer\UAS.cDa, Scer\GAL4da.G32 wings show anterior duplications but also have a truncated vein 2, an enlargement of the domain between vein 2 and the margin, and veins 3 and 4 are completely fused with a large delta at the margin. These flies also show an enhancement of the leg phenotype seen in Su(fu)Scer\UAS.cDa, Scer\GAL4da.G32 flies. Flies expressing Su(fu)Scer\UAS.cDa under the control of Scer\GAL4da.G32 in a fu1 background show the same phenotypes as those with a fu41 background.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Su(fu)Scer\UAS.cDa
Su(fu)UAS.cDa
Name Synonyms
Secondary FlyBase IDs
    References (2)