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General Information
Symbol
Dmel\cnk14C
Species
D. melanogaster
Name
FlyBase ID
FBal0193993
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
cnkC14
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C17418490T

Amino acid change:

Q253term | cnk-PA; Q253term | cnk-PB

Reported amino acid change:

Q253term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: Q253term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

cnk14C/Df(2R)BSC161 embryos derived from mothers bearing cnk14C mutant germline clones and thus lacking both maternal and zygotic cnk show a complete loss of muscle founder cells at stage 11/12.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

The lethality of cnk14C/Df(2R)BSC161 mutants is rescued by combination with cnkfTRG1248, whereas the lethality of cnk14C homozygous mutants is only partially rescued: some flies survive to adulthood but most die at the pupal stage.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)