Allele Dmel\kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG}

General Information
Symbol	Dmel\kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG}	Species	D. melanogaster
Name		FlyBase ID	FBal0194329
Feature type	allele	Associated gene	Dmel\kirre

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion, in vitro construct - deletion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Menon et al., 2005) in vitro construct - deletion (Menon et al., 2005) in vitro construct - regulatory fusion (Menon et al., 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of the kirre coding sequence lacking amino acids 103-553 (most of the extracellular region) and containing a T:Zzzz\FLAG tag downstream of the signal sequence. (Menon et al., 2005)
Carried in construct	P{UAS-kirre.flag(TM)CT} (Menon et al., 2005)
Tagged with	T:Zzzz\FLAG (Menon et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^how-24B does not have dominant negative effects. (Menon et al., 2005)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	kirre^{Δ610-959.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^how-24B, Scer\GAL4^how-24B, kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} rescues Df(1)w67k30 (Menon et al., 2005)
Fails to rescue	kirre^{Δ610-959.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^how-24B, Scer\GAL4^how-24B, kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} fails to rescue Df(1)w67k30 (Menon et al., 2005) Scer\GAL4^how-24B, Scer\GAL4^how-24B, kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} fails to rescue Df(1)w67k30 (Menon et al., 2005)
Comments	Expression of kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^how-24B does not restore the ability of myoblast founders to attract fusion-competent myoblasts in Df(1)w67k30 mutant embryos; myoblast fusion remains completely disrupted. Co-expression of kirre^{Δ610-959.Scer\UAS.T:Zzzz\FLAG} and kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^how-24B restores the ability of myoblast founders to attract fusion-competent myoblasts in Df(1)w67k30 mutant embryos. However, myoblast fusion stalls after precursors form. (Menon et al., 2005)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Menon et al., 2005, J. Cell Biol. 169(6): 909--920 A positive feedback loop between dumbfounded and rolling pebbles leads to myotube enlargement in Drosophila. [FBrf0187819]

Allele Dmel\kirreΔ103-553.Scer\UAS.T:Zzzz\FLAG

Allele Dmel\kirre^{Δ103-553.Scer\UAS.T:Zzzz\FLAG}