Allele Dmel\y^{P1\loxP.gyp-gyp}

General Information
Symbol	Dmel\y^{P1\loxP.gyp-gyp}	Species	D. melanogaster
Name		FlyBase ID	FBal0194356
Feature type	allele	Associated gene	Dmel\y

Allele class
Mutagen	in vitro construct
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct (Gilbert et al., 2006, Kuhn et al., 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	y^+mDint2 (Kuhn et al., 2004)
Nature of the lesion	Statement Reference Contains a gypsy\su(Hw)BR insulator between the y wing and body enhancers and the y gene. (Gilbert et al., 2006) A P1\loxP cassette containing a gypsy\su(Hw)BR insulator has been inserted between the y enhancers and the y transcription start site. (Kuhn et al., 2004)
Carried in construct	P{gyp-gyp} (Gilbert et al., 2006, Kuhn et al., 2004, Roy et al., 2007) P{gyp-Δgyp} (Kuhn et al., 2004)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective, with y¹ (Gilbert et al., 2006, Kuhn et al., 2004) body color defective (with y¹) (Gilbert et al., 2006)
Phenotype Manifest In
	adult cuticle, with y¹ (Gilbert et al., 2006, Kuhn et al., 2004) adult cuticle (with y¹) (Gilbert et al., 2006)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
NOT Enhanced by
Statement Reference y¹, y^{P1\loxP.gyp-gyp} has body color defective phenotype, non-enhanceable by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006) y^{P1\loxP.gyp-gyp}/y¹ has body color defective phenotype, non-enhanceable by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006)
NOT suppressed by
Statement Reference y¹, y^{P1\loxP.gyp-gyp} has body color defective phenotype, non-suppressible by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006) y^{P1\loxP.gyp-gyp}/y¹ has body color defective phenotype, non-suppressible by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006)
Phenotype Manifest In
NOT Enhanced by
Statement Reference y¹, y^{P1\loxP.gyp-gyp} has adult cuticle phenotype, non-enhanceable by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006) y^{P1\loxP.gyp-gyp}/y¹ has adult cuticle phenotype, non-enhanceable by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006)
NOT suppressed by
Statement Reference y¹, y^{P1\loxP.gyp-gyp} has adult cuticle phenotype, non-suppressible by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006) y^{P1\loxP.gyp-gyp}/y¹ has adult cuticle phenotype, non-suppressible by BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2}/Scer\GAL4^y.PG (Gilbert et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference Body colour: the level of pigmentation in the abdomen of y^{P1\loxP.gyp-gyp} flies is unaffected if they are also homozygous for BEAF-32^AB-KO. (Roy et al., 2007)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	y^{P1\loxP.gyp-gyp}
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Roy et al., 2007, Genetics 176(2): 801--813 Characterization of BEAF mutations isolated by homologous recombination in Drosophila. [FBrf0200670] Gilbert et al., 2006, Genetics 173(3): 1365--1375 The Drosophila boundary element-associated factors BEAF-32A and BEAF-32B affect chromatin structure. [FBrf0192350] Kuhn et al., 2004, Mol. Cell. Biol. 24(4): 1470--1480 Studies of the role of the Drosophila scs and scs' insulators in defining boundaries of a chromosome puff. [FBrf0167894]

Allele Dmel\yP1\loxP.gyp-gyp

Allele Dmel\y^{P1\loxP.gyp-gyp}