Allele Dmel\os^{Scer\UAS.T:Avic\GFP-EGFP}

General Information
Symbol	Dmel\os^{Scer\UAS.T:Avic\GFP-EGFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0194748
Feature type	allele	Associated gene	Dmel\os

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Hombria et al., 2005, Tsai and Sun, 2004) in vitro construct - regulatory fusion (Hombria et al., 2005, Tsai and Sun, 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of the open reading frame of os, which is tagged with T:Avic\GFP^EGFP. (Hombria et al., 2005) Scer\UAS regulatory sequences drive expression of os fused to T:Avic\GFP. (Tsai and Sun, 2004)
Carried in construct	P{UAS-upd.EGFP} (Hombria et al., 2005, Tsai and Sun, 2004)
Tagged with	T:Avic\GFP (Tsai and Sun, 2004) T:Avic\GFP^EGFP (Hombria et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	wing, with Scer\GAL4^Bx-MS1096 (Hombria et al., 2005)
Detailed Description
	Statement Reference Expression of os^{Scer\UAS.T:Avic\GFP-EGFP} in wing imaginal discs, driven by Scer\GAL4^Bx-MS1096, results in adults with wings of reduced size. (Hombria et al., 2005)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^Bx-MS1096, os^{Scer\UAS.T:Avic\GFP-EGFP} has wing phenotype, suppressible by dome^{ΔEXT.Scer\UAS}/Scer\GAL4^Bx-MS1096 (Hombria et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference Coexpression of the dome^{ΔEXT.Scer\UAS} transgene with os^{Scer\UAS.T:Avic\GFP-EGFP} (both under the control of Scer\GAL4^Bx-MS1096) suppresses the reduced wing phenotype seen when os^{Scer\UAS.T:Avic\GFP-EGFP} is expressed alone. Expression of os^{Scer\UAS.T:Avic\GFP-EGFP} in the spiracles, driven by Scer\GAL4^klu-G410, results in partial rescue of the Df(1)os1A2 spiracle defect. (Hombria et al., 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	os^{Scer\UAS.T:Avic\GFP-EGFP}/Scer\GAL4^ey.PH rescues os¹ (Tsai and Sun, 2004)
Comments	Expression of os[Scer\UAS.T:Avic\GFP-EGFP] under the control of Scer\GAL4[ey.PH] rescues the small-eye phenotype of os[1] mutant flies. (Tsai and Sun, 2004)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	os^{Scer\UAS.T:Avic\GFP-EGFP}
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Hombria et al., 2005, Dev. Biol. 288(2): 420--433 Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand. [FBrf0190126] Tsai and Sun, 2004, genesis 39(2): 141--153 Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. [FBrf0179489]

Allele Dmel\osScer\UAS.T:Avic\GFP-EGFP

Allele Dmel\os^{Scer\UAS.T:Avic\GFP-EGFP}