FB2021_01, released Feb 18, 2021

Allele: Dmel\upd1UAS.EGFP

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General Information
Symbol
Dmel\upd1UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0194748
Feature type
allele
Associated gene
Dmel\upd1
Associated Insertion(s)
Carried in Construct
P{UAS-upd1.EGFP}
Also Known As
UAS-upd-GFP
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Hombria et al., 2005, Tsai and Sun, 2004)
in vitro construct - coding region fusion
(Hombria et al., 2005, Tsai and Sun, 2004)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-upd1.EGFP}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UASt regulatory sequences drive expression of the open reading frame of upd1, which is tagged with EGFP.

      (Hombria et al., 2005)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      upd1
      Tagged with
      EGFP
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of upd1Scer\UAS.T:Avic\GFP-EGFP in wing imaginal discs, driven by Scer\GAL4Bx-MS1096, results in adults with wings of reduced size.

      (Hombria et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4Bx-MS1096, upd1UAS.EGFP has wing phenotype, suppressible by domeΔEXT.UAS/Scer\GAL4Bx-MS1096

      (Hombria et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of the domeΔEXT.Scer\UAS transgene with upd1Scer\UAS.T:Avic\GFP-EGFP (both under the control of Scer\GAL4Bx-MS1096) suppresses the reduced wing phenotype seen when upd1Scer\UAS.T:Avic\GFP-EGFP is expressed alone.

      Expression of upd1Scer\UAS.T:Avic\GFP-EGFP in the spiracles, driven by Scer\GAL4klu-G410, results in partial rescue of the Df(1)os1A2 spiracle defect.

      (Hombria et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      upd1UAS.EGFP/Scer\GAL4ey.PH rescues upd11

      (Tsai and Sun, 2004)

      upd1UAS.EGFP/Scer\GAL4ey.PH rescues Df(1)os1

      (Tsai and Sun, 2004)
      Comments

      Expression of upd1Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4ey.PH rescues the small-eye phenotype of Df(1)os1 mutant flies.

      (Tsai and Sun, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      osScer\UAS.T:Avic\GFP-EGFP
      upd1Scer\UAS.T:Avic\GFP-EGFP
      upd1UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)