FB2025_01 , released February 20, 2025
Allele: Dmel\pegRNAi.Sym.UAS
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General Information
Symbol
Dmel\pegRNAi.Sym.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0194759
Feature type
allele
Associated gene
Dmel\peg
Associated Insertion(s)
Carried in Construct
P{Sym-UAS-peg}
Key Links
Transgenic product class
RNAi_reagent
(Mohit et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Mohit et al., 2006)
Mutagen
in vitro construct
(Mohit et al., 2006)
Progenitor genotype
Carried in construct
P{Sym-UAS-peg}
Cytology
Description

Sense-antisense transcription (driven by two convergent arrays of UAS regulatory sequences) of CG17278 base pairs 1201--1569, corresponding to the 3' end of CG17278 (coordinates according to clone SD04019) results in double stranded RNA (dsRNA) expression.

(Mohit et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
peg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of CG17278dsRNA.Sym.Scer\UAS under the control of Scer\GAL4ptc-559.1, does not cause phenotypes in the cuticle or imaginal discs.

      Simultaneous expression of CG17278Sym.Scer\UAS and CG17278a.Sym.Scer\UAS (both carried on P{Sym-UAS-CG17278}) under the control of Scer\GAL4ptc-559.1, does not cause phenotypes in the cuticle or imaginal discs.

      (Mohit et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Suppressor of
      Statement
      Reference

      Scer\GAL4vg.PM/pegRNAi.Sym.UAS is a suppressor of wing disc phenotype of Scer\GAL4vg.PM, sggUAS.cSa

      (Mohit et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Simultaneous expression of Cyp310a1Sym.Scer\UAS and Cyp310a1a.Sym.Scer\UAS (both carried on P{Sym-UAS-Cyp310a1}) and CG17278Sym.Scer\UAS and CG17278a.Sym.Scer\UAS (both carried on P{Sym-UAS-CG17278}) do not cause any observable phenotypes.

      Simultaneous expression of CG17278Sym.Scer\UAS and CG17278a.Sym.Scer\UAS (both carried on P{Sym-UAS-CG17278}) to create CG17278 dsRNA results in an enhancement of the notum-to-wing pouch transformation within the dorsal mesothoracic disc in flies expressing dshScer\UAS.cNa, under the control of Scer\GAL4ptc-559.1.

      Simultaneous expression of CG17278Sym.Scer\UAS and CG17278a.Sym.Scer\UAS (both carried on P{Sym-UAS-CG17278}) to create CG17278 dsRNA results in a suppression of the reduction in wing pouch size seen when sggScer\UAS.cSa is expressed under the control of Scer\GAL4vg.PM.

      Simultaneous expression of Cyp310a1dsRNA.Sym.Scer\UAS and CG17278dsRNA.Sym.Scer\UAS do not cause any observable phenotypes.

      (Mohit et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      CG17278Sym.Scer\UAS
      CG17278dsRNA.Sym.Scer\UAS
      CG17278dsRNA.Sym.UAS
      pegRNAi.Sym.UAS
      pegdsRNA.Sym.UAS
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0194758
      References (2)