FB2025_01 , released February 20, 2025
Allele: Dmel\Tpisgk-1.UAS
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General Information
Symbol
Dmel\Tpisgk-1.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0195207
Feature type
allele
Associated gene
Dmel\Tpi
Associated Insertion(s)
Carried in Construct
P{UAS-Tpi.sgk1}
Key Links
Transgenic product class
missense_variant
(Celotto et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Celotto et al., 2006)
Mutagen
in vitro construct
(Celotto et al., 2006)
Progenitor genotype
Tpisgk-1
(Celotto et al., 2006)
Carried in construct
P{UAS-Tpi.sgk1}
Cytology
Description

UAS regulatory sequences drive expression of nucleotides 57-1371 of Tpisgk-1.

(Celotto et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tpi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Tpisgk-1.Scer\UAS under the control of Scer\GAL4Act5C.PI show no significant decrease in lifespan compared to controls.

      Flies expressing Tpisgk-1.Scer\UAS under the control of Scer\GAL4Act5C.PI do not have a bang sensitive phenotype at either room temperature or at 29[o]C.

      (Seigle et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Act5C.PI/Tpisgk-1.UAS partially rescues Tpisgk-1

      (Seigle et al., 2008)
      Fails to rescue

      Scer\GAL4Act5C.PI/Tpisgk-1.UAS fails to rescue Tpisgk-1

      (Celotto et al., 2006)
      Comments

      Expression of Tpisgk-1.Scer\UAS under the control of Scer\GAL4Act5C.PI partially rescues the reduced median lifespan of Tpisgk-1 homozygotes.

      (Seigle et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tpisgk-1.Scer\UAS
      Tpisgk-1.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)