FlyBase Allele Report: Dmel\sra[cHa]

General Information

Symbol

Dmel\sra^cHa

Species

D. melanogaster

Name

construct of Horner

FlyBase ID

FBal0195463

Feature type

allele

Associated gene

Dmel\sra

Associated Insertion(s)

Carried in Construct

P{sra^cHa}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Horner, 2006)

Progenitor genotype

Carried in construct

P{sra^cHa}

Cytology

Description

Consists of genomic sequences from the intron of the Bin1 gene to approximately 1100bp into the sra intron, followed by a region within the sra intron that is about 170bp upstream of the splice acceptor site to a position in the 3' UTR of the CG6126 gene. The resulting transgene has all sra codons but lacks the majority of the sra intron, and has the entire intergenic regions separating sra from its flanking genes, plus 22 codons of Bin1 but no coding sequence from CG6126.

(Horner, 2006)

Allele components

Component

Use(s)

Encoded product / tool

sra

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

sra^cHa is a non-suppressor of lethal | heat sensitive phenotype of Bin1^R7-18

(Horner, 2006)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The sra^cHa transgene does not rescue the Bin1^R7-18 mutation.

(Horner, 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

sra^cHa rescues sra^A108

(Horner, 2006)

sra^cHa rescues sra^A426

(Horner, 2006)

sra^cHa rescues sra⁶¹⁹

(Horner, 2006)

sra^cHa rescues sra⁰⁵²⁰³

(Horner, 2006)

sra^cHa rescues sra^UM3

(Horner, 2006)

sra^cHa rescues sra⁶⁸⁷

(Horner, 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sra^cHa

Name Synonyms

construct of Horner

Secondary FlyBase IDs

References (1)

Report Sections

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