FB2025_01 , released February 20, 2025
Allele: Dmel\bmmUAS.EGFP
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General Information
Symbol
Dmel\bmmUAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0195577
Feature type
allele
Associated gene
Dmel\bmm
Associated Insertion(s)
Carried in Construct
P{UAS-bmm.EGFP}
Key Links
Transgenic product class
inframe_deletion
(Gronke et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Gronke et al., 2005)
Mutagen
in vitro construct
(Gronke et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-bmm.EGFP}
Cytology
Description

UASt regulatory sequences drive expression of a bmm cDNA coding for amino acids 1-507 and tagged with EGFP.

(Gronke et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
bmm
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  obesity
      modeled by Grasp65302
      (Kim et al., 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of bmmScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4fat depletes organismal triacylglycerol storage and reduces both the number and size of lipid droplets in fat body cells of immature adult flies.

      (Gronke et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      bmmUAS.EGFP/Scer\GAL4GMR.PU is a suppressor | partially of retina phenotype of mir-210Δ

      (Weigelt et al., 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      bmmUAS.EGFP/Scer\GAL4Act5C.PI rescues bmm1

      (Gronke et al., 2005)
      Comments

      Expression of bmmScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4Act5C.PI reverts the obese phenotype of bmm1 mutant flies.

      (Gronke et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bmmScer\UAS.T:Avic\GFP-EGFP
      bmmUAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (4)