FB2025_01 , released February 20, 2025
Allele: Dmel\wmdKG07581
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General Information
Symbol
Dmel\wmdKG07581
Species
D. melanogaster
Name
FlyBase ID
FBal0195712
Feature type
allele
Associated gene
Dmel\wmd
Associated Insertion(s)
P{SUPor-P}wmdKG07581
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{SUPor-P}wmdKG07581
    Cytology
    Description

    Insertion close to the start site of wmd.

    (Dworkin and Gibson., 2006)
    Allele components
    Component
    Use(s)
    Inserted element
    P{SUPor-P}
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        wmdKG07581/Df(2R)BSC661 adult flies show wing defects.

        (Borg et al., 2016)

        Df(2R)BSC785 failed to complement wmdKG07581 for a visible wing phenotype.

        (Christensen et al., 2009.5.6)

        Approximately 50% of homozygotes die as pharate adults, appearing to develop normally but failing to eclose.

        (Dworkin, 2007.1.29)

        Homozygotes/hemizygotes have wing morphogenesis defects consistent with improper lamination of the dorsal and ventral wing surfaces.

        Heterozygotes show a direct effect on the shape of the wing.

        (Dworkin and Gibson, 2006)

        Homozygotes show a failure of proper wing expansion. In particular, the dorsal and ventral layers of the wing do not show proper lamination, resulting in a variety of phenotypes ranging from a relatively mild convexity in the wing, with regional "wrinkles" where there is local failure in lamination, to strong blistering phenotypes or unexpanded wings.

        (Dworkin and Gibson., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        kg07581
        (Dworkin and Gibson, 2006, Dworkin and Gibson., 2006)
        wmdKG07581
        (Christensen et al., 2009.5.6)
        wmdMatt
        (Borg et al., 2016)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)