Allele Dmel\ihog^KG

General Information
Symbol	Dmel\ihog^KG	Species	D. melanogaster
Name		FlyBase ID	FBal0195789
Feature type	allele	Associated gene	Dmel\ihog

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Yao et al., 2006)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{SUPor-P}CG10158^KG05348 (Yao et al., 2006)
Nature of the lesion	Statement Reference Imprecise excision of the P{SUPor-P} element, resulting in deletion from +1979 of the iHog coding sequence to the original P{SUPor-P} insertion site. This removes the sequence encoding the transmembrane domain of the iHog protein and some of the 5'UTR of the CG10158 gene. (Yao et al., 2006)
Caused by aberration	Df(2L)iHog^KG (Yao et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	denticle belt \| embryonic stage (with ihog^e02142) (Yao et al., 2006) denticle belt \| embryonic stage \| maternal effect (Yao et al., 2006) wing (Yao et al., 2006)
Detailed Description
	Statement Reference iHog^KG maternal germ-line clones produce embryos with denticle belt fusions. In contrast, zygotically homozygous iHog^e02142 embryos exhibit no cuticle phenotype. Embryos from iHog^KG maternal germ-line clones with paternally-provided iHog^e02142 show less severe denticle belt fusions. Flies carrying iHog^KG clones show a decrease in the extent of the intervein region between L3 and L4 in the wing. (Yao et al., 2006)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference ihog^KG has denticle belt \| embryonic stage phenotype, enhanceable by dlp^A187 (Yao et al., 2006)
NOT Suppressor of
Statement Reference ihog^KG/ihog^KG is a non-suppressor of denticle belt \| embryonic stage phenotype of ptc⁹ (Yao et al., 2006, Yao et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference In contrast to zygotic iHog^KG single mutants, iHog^KG; dlp^A187 zygotic double mutants show denticle belt fusions. Embryos with maternal/zygotic iHog^KG and zygotic ptc⁹ show the denticle belt duplication phenotype of ptc⁹ single mutants and not the denticle belt fusion phenotype of iHog^KG maternal/zygotic single mutants. (Yao et al., 2006)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	Associated with: CG10158^KG. (Yao et al., 2006)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	iHog^KG (Yao et al., 2006) ihog^KG
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Yao et al., 2006, Cell 125(2): 343--357 The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. [FBrf0189929]

Allele Dmel\ihogKG

Allele Dmel\ihog^KG