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General Information
Symbol
Dmel\X11LUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Matsuno
FlyBase ID
FBal0195804
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a full-length X11L cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of X11LScer\UAS.cMa in the developing optic lobe and eye disc, driven by Scer\GAL4MZ1369, results in the formation of rough eyes. Rhabdomeres in these flies are not restricted to the distal side of the fenestrated membrane, as in wild-type flies, but are found beneath this structure, displacing the lamina.

Pupal eyes that express X11LScer\UAS.cMa under the control of Scer\GAL4MZ1369 frequently display fused ommatidia, misplaced bristle complexes and reduced numbers of cone cells from four to two or even to a single cell. One or both of the primary pigment cells are sometimes missing after apparently having failed to differentiate properly.

Expression of X11LScer\UAS.cMa under the control of Scer\GAL4GMR.PY results in defects in eye morphology. Eye discs of these animals show an increase in cell death compared to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
X11LScer\UAS.cMa
X11LUAS.cMa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Matsuno
Secondary FlyBase IDs
    References (2)