FB2025_01 , released February 20, 2025
Allele: Dmel\pyd3Lb10
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General Information
Symbol
Dmel\pyd3Lb10
Species
D. melanogaster
Name
FlyBase ID
FBal0196005
Feature type
allele
Associated gene
Dmel\pyd3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Rawls, 2006)
Progenitor genotype
P{GawB}NP2343
(Rawls, 2006)
Cytology
Description

Imprecise excision of the P{GawB}NP2343 insertion, resulting in a 1732bp deletion of genomic sequences extending 792bp 5' to the apparent pyd3 transcription start site and 941bp into the transcribed region of pyd3.

(Rawls, 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:7,749,148..7,750,880 [-]
Comment:

1732 bp deletion associated with the imprecise excision of P{GawB}NP2343, resulting in the loss of 792 bp 5' to the pyd3 gene transcription start and 941 bp downstream (annotated boundaries approximate).

(Rawls, 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous flies appear morphologically normal.

      (Rawls, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      pyd3+t3.8, pyd3Lb10, Adcb-1 is a suppressor | partially of visible | heat sensitive phenotype of Dcr-2UAS.cDa, EogtGD5084, Scer\GAL4en.PU

      (Müller et al., 2013)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      pyd3+t3.8/pyd3Lb10 is a suppressor | partially of wing blade posterior compartment | heat sensitive phenotype of Dcr-2UAS.cDa, EogtGD5084, Scer\GAL4en.PU

      (Müller et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      b1 ; pyd3+t3.8 ; pyd3Lb10 partially suppresses the wing blistering phenotype seen in the posterior compartment of wings in flies expressing EogtGD5084 under the control of Scer\GAL4en.PU in the presence of Dcr-2Scer\UAS.cDa at 27[o]C.

      (Müller et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pyd3Lb10
      (Müller et al., 2013, Rawls, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)