FB2025_01 , released February 20, 2025
Allele: Dmel\JYalpha8c
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General Information
Symbol
Dmel\JYalpha8c
Species
D. melanogaster
Name
FlyBase ID
FBal0197105
Feature type
allele
Associated gene
Dmel\JYalpha
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Masly et al., 2006)
Progenitor genotype
JYalphaKG09295
(Masly et al., 2006)
Cytology
Description

Imprecise excision of the insertion in JYalphaKG09295, resulting in a protein that is truncated after the first 268 amino acids.

(Masly et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous males show sterility (as assayed by the degree of sperm motility).

      (Masly et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      JYalpha8c results in hybrid sterility (as assayed by the degree of sperm motility) when heterozygous in males containing the D.simulans 4th chromosome introgressed into an otherwise D.melanogaster background.

      (Masly et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      JYAlphamel.8c
      (Masly et al., 2006)
      JYalpha8c
      Name Synonyms
      Secondary FlyBase IDs
        References (1)