A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\ss134

General Information
SymbolDmel\ss134SpeciesD. melanogaster
NameFlyBase IDFBal0197113
Feature typealleleAssociated geneDmel\ss
Allele class
Mutagenethyl methanesulfonate
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Description
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FB2013_03
FB2013_02
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Allele class
Mutagen
Mutations Mapped to the Genome
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Cytology
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dendrite & dorsal multidendritic neuron ddaB | somatic clone
dendrite & dorsal multidendritic neuron ddaD | somatic clone
dendrite & dorsal multidendritic neuron ddaE
dendrite & dorsal multidendritic neuron ddaE (with ssD115.7)
dendrite & dorsal multidendritic neuron ddaE | somatic clone
dendrite & dorsal multidendritic neuron ddaF | somatic clone
dendrite & lateral multidendritic neuron ldaB | somatic clone
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Statement
Reference
Late stage ss134 embryos show defects in class I dendrite morphogenesis; primary branch overgrowth and increased terminal branching of the class I dendrites is seen. This defect persists throughout the third larval instar. ss134/ssD115.7 mutants show defects in class I dendrite morphogenesis; primary branch overgrowth and increased terminal branching of the class I dendrites is seen. ss134/ssaBR30-71 adults show a reduction in the size of bristles and an antenna-to-leg transformation. Single cell ss134 clones (generated using the MARCM technique) of the ddaE neuron show increased terminal branching, while the outgrowth of primary dendrites is mostly unaffected. Single cell ss134 clones (generated using the MARCM technique) of the ddaD neuron show increased branching and dendrite routing defects. Secondary dendrites are misoriented and branches improperly terminate posterior to the cell body. Single cell ss134 clones (generated using the MARCM technique) of the ddaB neuron show increased dendritic branching at the distal tips of primary and secondary dendrites. Single cell ss134 clones (generated using the MARCM technique) of the ldaB neuron show a reduction of dendritic spikes along all major branches. Single cell ss134 clones (generated using the MARCM technique) of the ddaF neuron show a reduction in the number of dendritic spikes and show clusters of longer terminal branches along the primary dendrites.
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Research paper
Parrish et al., 2009, Neuron 63(6): 788--802
The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. [FBrf0208858]
Kim et al., 2006, Genes Dev. 20(20): 2806--2819
The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. [FBrf0195191]