C25984852T
Q370term | Nf1-PB; Q370term | Nf1-PC; Q370term | Nf1-PD; Q370term | Nf1-PE; Q370term | Nf1-PF
Q370term
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Amino acid replacement: Q370term.
learning defective | adult stage (with Nf1E1)
size defective | pupal stage (with Nf1E1)
small body | pupal stage (with Nf1P2)
NMJ bouton | larval stage | supernumerary (with Nf1E1)
Mutant larvae ingest similar amounts of food as control larvae, but are smaller in size. As occurs in wild type, the mutant larvae do not wander from a food source.
The timing of pupariation is normal in Nf1E1/Nf1E2 animals, but they show an approximately 25% weight reduction compared to controls at the end of the larval stage.
Nf1E1/Nf1E2 do not show altered longevity compared to controls.
Mutant third instar larvae show an increase in mean number of boutons per neuromuscular junction compared to controls.
Bouton number per muscle area is significantly increased compared to wild type at the neuromuscular junction (NMJ) in homozygous and Nf1E1/Nf1E2 larvae.
The amplitude of the evoked junctional potential (EJP) at the NMJ is significantly increased in homozygous larvae compared to wild type, while the amplitude of the spontaneous mEJP is unaffected. The quantal content at the mutant NMJs is thus increased compared to wild type.
The amplitude of the evoked junctional potential (EJP) at the NMJ is significantly increased in Nf1E1/Nf1E2 larvae compared to wild type.
Homozygous pupae are 15-20% smaller than wild-type controls. Heterozygous pupae also show a small but highly significant reduction in length compared to controls.
The surface area of the wing in homozygotes is only 57% that of control flies.
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)Exel8034/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by +/Df(2L)BSC188
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2R)BSC639/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2R)Exel6059/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)Exel6024/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)BSC216/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)BSC240/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)Exel7043/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)Exel6025/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED800/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED1050/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by +/Df(1)ED7229
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED1004/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Pka-C1[+]/Pka-C1BG02142
Nf1E2 has small body | pupal stage phenotype, enhanceable by Pka-C1[+]/Pka-C106353
Nf1E2 has small body | pupal stage phenotype, enhanceable by Pka-C1B3
Nf1E2 has small body | pupal stage phenotype, enhanceable by nAChRα6DAS1
Nf1E2 has small body | pupal stage phenotype, enhanceable by nAChRα6DAS2
Nf1E2 has small body | pupal stage phenotype, enhanceable by nAChRα6KG05852
Nf1E2 has small body | pupal stage phenotype, enhanceable by Cul3gft2
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(1)BSC646/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by +/Df(2L)ED280
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED6569/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED353/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED1305/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)ED108/+
Nf1E2 has small body | pupal stage phenotype, enhanceable by Df(2L)BSC148/+
Nf1E2 has size defective | dominant | pupal stage phenotype, enhanceable by jebUAS.cVa/Scer\GAL4elav-C155
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(1)ED6574/+
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(1)ED11354/+
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(2R)BSC154/+
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(1)ED7261/+
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(2L)BSC312/+
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by +/Df(2L)BSC692
Nf1E2 has small body | pupal stage phenotype, non-enhanceable by Df(2L)BSC206/+
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, non-enhanceable by spi1/spi[+]
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6291/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC581/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)ED6802/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC658/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC725/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC834/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC823/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6234/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC763/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC572/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC583/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6251/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC147/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2L)Exel7038
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)Exel7010/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC256/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2L)Exel7080
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC107/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC105/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC244/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)Exel9064/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC215/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)Exel6045/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC307/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC383/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel7158/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC262
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC334
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC131/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC271
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC152/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC338/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC268/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC429/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC279/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC404/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC777/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC158
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC821/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC406/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC264/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)Exel7173
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel6065/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel7128/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel7098/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC699
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel7124/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC231/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC701
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC339/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)Exel7144/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)Exel6064
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC199/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(2R)BSC161
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC710/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC656/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)ED447/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel9051/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel7464/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)BSC302/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)Exel6047/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(1)Exel6221
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(1)ED6396
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2L)Exel8041/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6254/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC533/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6290/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel9068/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(2R)BSC607/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(1)BSC275
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC719/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel8196/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC589/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Alk8
Nf1E2 has small body | pupal stage phenotype, suppressible by Alk9
Nf1E2 has small body | pupal stage phenotype, suppressible by jebweli/jeb[+]
Nf1E2 has small body | pupal stage phenotype, suppressible by cnk[+]/cnkXE-385
Nf1E2 has small body | pupal stage phenotype, suppressible by cnk[+]/cnkE-2083
Nf1E2 has small body | pupal stage phenotype, suppressible by Dsor1[+]/Dsor1LH110
Nf1E2 has small body | pupal stage phenotype, suppressible by amx[+]/amxf06362
Nf1E2 has small body | pupal stage phenotype, suppressible by dncM14/dnc[+]
Nf1E2 has small body | pupal stage phenotype, suppressible by dncML/dnc[+]
Nf1E2 has small body | pupal stage phenotype, suppressible by dnc1
Nf1E2 has small body | pupal stage phenotype, suppressible by Dap160[+]/Dap160Δ1
Nf1E2 has small body | pupal stage phenotype, suppressible by Dap160[+]/Dap160Δ2
Nf1E2 has small body | pupal stage phenotype, suppressible by elav[+]/elavG0031
Nf1E2 has small body | pupal stage phenotype, suppressible by elav[+]/elav1
Nf1E2 has small body | pupal stage phenotype, suppressible by carΔ146
Nf1E2 has small body | pupal stage phenotype, suppressible by car1
Nf1E2 has small body | pupal stage phenotype, suppressible by dor8/dor+
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/jebKK111857
Nf1E2 has small body | pupal stage phenotype, suppressible by jebKK111857/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by jebKK111857/Scer\GAL4nSyb.PS
Nf1E2 has small body | pupal stage phenotype, suppressible | partially by Scer\GAL4repo/jebKK111857
Nf1E2 has small body | pupal stage phenotype, suppressible by AlkKK102942/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, suppressible by AlkKK102942/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by AlkKK102942/Scer\GAL4nSyb.PS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/Dsor1KK102276
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4nSyb.PS/Dsor1GD9123
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/amxGD1168
Nf1E2 has small body | pupal stage phenotype, suppressible by amxGD1168/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by cnkKK109209/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, suppressible by cnkKK109209/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by CCKLR-17D1KK108482/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, suppressible by CCKLR-17D1KK108482/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by Dap160KK102297/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, suppressible by Dap160KK102297/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by Dap160KK102297/Scer\GAL4nSyb.PS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/Rab9KK109041
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4C23/Rab9KK109041
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Act5C.PU/Rab9S26N.UASp.YFP
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4nSyb.PS/Rab9S26N.UASp.YFP
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4C23/Rab9S26N.UASp.YFP
Nf1E2 has small body | pupal stage phenotype, suppressible by Dcr-2UAS.cDa/Scer\GAL4Ras64B.PW/NAAT1KK112890
Nf1E2 has small body | pupal stage phenotype, suppressible by NAAT1KK112890/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4nSyb.PS/NAAT1KK112890
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/HERC2KK100181
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Ras64B.PW/Hs3st-BKK108793
Nf1E2 has small body | pupal stage phenotype, suppressible by Hs3st-BKK108793/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Act5C.PU/dncKK108541
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Feb36/dncKK108541
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Aug21/dncKK108541
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Akh.PW/dncKK108541
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, suppressible by Alk9/Alk[+]
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, suppressible by jebweli/jeb[+]
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, suppressible by cnk[+]/cnkXE-385
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, suppressible by Df(1)Exel9051/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Aug21/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Akh.PW/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Feb36/Mmus\Prkacaact.3xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Aug21/Mmus\Prkacaact.3xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Akh.PW/Mmus\Prkacaact.3xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Aug21/Mmus\Prkacaact.4xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Akh.PW/Mmus\Prkacaact.4xUAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4Akh.PW/Mmus\PrkacamC.UAS
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6255/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)ED7294/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6231/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6223/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC723/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC310/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(1)BSC866
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6237/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel9049/+
Nf1E2 has small body | pupal stage phenotype, suppressible by +/Df(1)BSC626
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC657/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)Exel6241/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC546/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC628/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC706/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC582/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC708/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC755/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC853/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC536/+
Nf1E2 has small body | pupal stage phenotype, suppressible by Df(1)BSC705/+
Nf1E2 has size defective | pupal stage phenotype, suppressible | partially by Alk1/Alk[+]
Nf1E2 has learning defective | adult stage phenotype, suppressible | partially by Alk1/Alk[+]
Nf1E2 has size defective | pupal stage phenotype, suppressible | partially by Alk9/Alk[+]
Nf1E2 has learning defective | adult stage phenotype, suppressible | partially by Alk9/Alk[+]
Nf1E2 has size defective | recessive | pupal stage phenotype, suppressible | partially by Scer\GAL4elav-C155/AlkEC.UAS.Tag:MYC
Nf1E2 has size defective | recessive | pupal stage phenotype, suppressible | partially by AlkEC.UAS.Tag:MYC/Scer\GAL4Ras64B.PW
Nf1E2 has size defective | recessive | pupal stage phenotype, suppressible | partially by AlkEC.UAS.Tag:MYC/Scer\GAL4386Y
Nf1E2 has size defective | recessive | larval stage phenotype, suppressible | partially by Scer\GAL4elav-C155/AlkGD42
Nf1E2 has size defective | recessive | larval stage phenotype, suppressible | partially by AlkGD42/Scer\GAL4Ras64B.PW
Nf1E2 has decreased cell size | adult stage phenotype, suppressible | partially by AlkGD42/Scer\GAL4Ras64B.PW
Nf1E2 has size defective | recessive | larval stage phenotype, suppressible | partially by AlkGD42/Scer\GAL4386Y
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by Scer\GAL4elav-C155/AlkEC.UAS.Tag:MYC
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by AlkEC.UAS.Tag:MYC/Scer\GAL4Ras64B.PW
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by AlkEC.UAS.Tag:MYC/Scer\GAL4Alk.38
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by Scer\GAL4elav-C155/AlkGD42
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by AlkGD42/Scer\GAL4Ras64B.PW
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, suppressible by AlkGD42/Scer\GAL4Alk.38
Nf1E2 has small body | pupal stage phenotype, suppressible | partially by phl[+]/Raf12/Ras85D[+]/Ras85Dunspecified
Nf1E2 has small body | pupal stage phenotype, suppressible | partially by rl[+]/rl1/phl[+]/Raf12
Nf1E2 has small body | pupal stage phenotype, suppressible by Scer\GAL4elav-C155/vapUAS.Tag:MYC
Nf1E2 has small body | pupal stage phenotype, suppressible by vapUAS.Tag:MYC/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, non-suppressible by InR05545
Nf1E2 has small body | pupal stage phenotype, non-suppressible by InR327
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(1)ED6574/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(1)ED11354/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(2R)BSC154/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(1)ED7261/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(2L)BSC312/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by +/Df(2L)BSC692
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(2L)BSC206/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by AlkKK102942/Scer\GAL4repo
Nf1E2 has small body | pupal stage phenotype, non-suppressible by CCKLR-17D1KK108482/Scer\GAL4repo
Nf1E2 has small body | pupal stage phenotype, non-suppressible by CCKLR-17D3GD3431/Scer\GAL4Ras64B.PW
Nf1E2 has small body | pupal stage phenotype, non-suppressible by CCKLR-17D3GD3431/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, non-suppressible by CCKLR-17D3GD3431/Scer\GAL4repo
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Ret.PW/RetK805A.UAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4repo/NAAT1KK112890
Nf1E2 has small body | pupal stage phenotype, non-suppressible by HERC2KK100181/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4repo/Hs3st-BKK108793
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4elav.PU/dncKK108541
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Ras64B.PW/dncKK108541
Nf1E2 has small body | pupal stage phenotype, non-suppressible by dncKK108541/Scer\GAL4C23
Nf1E2 has neuroanatomy defective | third instar larval stage phenotype, non-suppressible by spi1/spi[+]
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Feb36/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4elav.PU/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Ras64B.PW/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4C23/Mmus\Prkacaact.2xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4elav.PU/Mmus\Prkacaact.3xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Ras64B.PW/Mmus\Prkacaact.3xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Mmus\Prkacaact.3xUAS/Scer\GAL4C23
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4elav.PU/Mmus\Prkacaact.4xUAS
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Mmus\Prkacaact.4xUAS/Scer\GAL4C23
Nf1E2 has size defective | recessive | larval stage phenotype, non-suppressible by Scer\GAL4ey-OK107/AlkEC.UAS.Tag:MYC
Nf1E2 has size defective | recessive | larval stage phenotype, non-suppressible by Scer\GAL4ey-OK107/AlkGD42
Nf1E2 has size defective | recessive | larval stage phenotype, non-suppressible by AlkEC.UAS.Tag:MYC/Scer\GAL4CCAP.PP
Nf1E2 has size defective | recessive | larval stage phenotype, non-suppressible by Scer\GAL4CCAP.PP/AlkGD42
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, non-suppressible by Scer\GAL4c747/AlkEC.UAS.Tag:MYC
Nf1E1/Nf1E2 has learning defective | adult stage phenotype, non-suppressible by Scer\GAL4c747/AlkGD42
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Df(3L)GN34/+
Nf1E2 has small body | pupal stage phenotype, non-suppressible by +/Df(3L)GN19
Nf1E2 has small body | pupal stage phenotype, non-suppressible by vapUAS.Tag:MYC/Scer\GAL4repo
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4elav-C155/RasGAP1UAS.cWa
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4Ras64B.PW/RasGAP1UAS.cWa
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Scer\GAL4repo/RasGAP1UAS.cWa
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Ras85D[+]/Ras85Dunspecified
Nf1E2 has small body | pupal stage phenotype, non-suppressible by RglBG02025
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Ralaunspecified
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Pi3K21BEY06407
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Ras64Bunspecified/Ras85D[+]/Ras85Dunspecified
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Dsor1[+]/Ras85D[+]/Ras85Dunspecified/Dsor1S-1221
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Ras64Bunspecified/Dsor1[+]/Ras64B[+]/Dsor1S-1221
Nf1E2 has small body | pupal stage phenotype, non-suppressible by Ras64Bunspecified/phl[+]/Ras64B[+]/Raf12
Nf1E2 is a non-enhancer of large body | heat sensitive phenotype of Ilp2hs.PR
Nf1E2 is a non-suppressor of large body | heat sensitive phenotype of Ilp2hs.PR
Dsor1KK102276, Nf1E2, Scer\GAL4repo has lethal phenotype
Dsor1KK102276, Nf1E2, Scer\GAL4C23 has lethal phenotype
Dsor1GD9123, Nf1E2, Scer\GAL4Ras64B.PW has lethal phenotype
Dsor1GD9123, Nf1E2, Scer\GAL4C23 has lethal phenotype
Dap160KK102297, Nf1E2, Scer\GAL4repo has lethal phenotype
Nf1E2, Scer\GAL4Act5C.PU, dncKK108541 has lethal - all die during pupal stage phenotype
Mmus\Prkacaact.2xUAS, Nf1E2, Scer\GAL4Act5C.PU has partially lethal phenotype
Mmus\Prkacaact.3xUAS, Nf1E2, Scer\GAL4Act5C.PU has lethal phenotype
Mmus\Prkacaact.4xUAS, Nf1E2, Scer\GAL4Act5C.PU has lethal phenotype
Mmus\Prkacaact.4xUAS, Nf1E2, Scer\GAL4Feb36 has lethal phenotype
Mmus\Prkacaact.4xUAS, Nf1E2, Scer\GAL4Ras64B.PW has lethal phenotype
Mmus\Prkacaact.4xUAS, Nf1E2, Scer\GAL4C23 has lethal - all die during pupal stage phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4Act5C.PU has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4elav.PU has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4Ras64B.PW has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4C23 has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4Feb36 has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4Aug21 has lethal phenotype
Mmus\PrkacamC.UAS, Nf1E2, Scer\GAL4Akh.PW has partially lethal phenotype
FakN30/FakKG00304, Nf1[+]/Nf1E2 has neuroanatomy defective | larval stage phenotype
AlkUAS.cLa, Nf1E2, Scer\GAL4elav-C155 has lethal | recessive | larval stage phenotype
AlkUAS.cLa, Nf1E2, Scer\GAL4Ras64B.PW has lethal | recessive | larval stage phenotype
Alkact.UAS.Tag:HA, Nf1E2, Scer\GAL4elav-C155 has lethal | dominant | larval stage phenotype
AlkUAS.cLa, Nf1E2, Scer\GAL4386Y has lethal | recessive | larval stage phenotype
AlkUAS.cLa, Nf1E2, Scer\GAL4elav-C155 has lethal | dominant | larval stage phenotype
Nf1E2, Scer\GAL4elav-C155, jebUAS.cVa has lethal | recessive | larval stage phenotype
Nf1E2, Scer\GAL4Ras64B.PW, jebUAS.cVa has lethal | recessive | larval stage phenotype
Nf1E2, Scer\GAL4386Y, jebUAS.cVa has lethal | recessive | larval stage phenotype
Alkact.UAS.Tag:HA, Nf1E2, Scer\GAL4elav-C155 has lethal | recessive | larval stage phenotype
Alkact.UAS.Tag:HA, Nf1E2, Scer\GAL4Ras64B.PW has lethal | recessive | larval stage phenotype
Alkact.UAS.Tag:HA, Nf1E2, Scer\GAL4386Y has lethal | recessive | larval stage phenotype
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, non-enhanceable by spi1/spi[+]
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, suppressible by Alk9/Alk[+]
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, suppressible by jebweli/jeb[+]
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, suppressible by cnk[+]/cnkXE-385
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, suppressible by Df(1)Exel9051/+
Nf1E2 has wing phenotype, suppressible | partially by AlkGD42/Scer\GAL4Ras64B.PW
Nf1E2 has NMJ bouton | supernumerary | third instar larval stage phenotype, non-suppressible by spi1/spi[+]
FakN30/FakKG00304, Nf1[+]/Nf1E2 has NMJ bouton | supernumerary | larval stage phenotype
Nf1E2 has no effect on in the increased pupal length phenotype caused by expression of Ilp2hs.PR using heat shock.
Expression of jebKK111857 under the control of either Scer\GAL4Ras64B.PW, Scer\GAL4C23 or Scer\GAL4nSyb.PS suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of jebKK111857 under the control of Scer\GAL4repo partially suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of AlkKK102942 under the control of either Scer\GAL4Ras64B.PW, Scer\GAL4C23 or Scer\GAL4nSyb.PS suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of Scer\GAL4repo has no significant effect.
Expression of Dsor1KK102276 under the control of Scer\GAL4Ras64B.PW at 18[o]C suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of Dsor1GD9123 under the control of Scer\GAL4nSyb.PS suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of amxGD1168 under the control of either Scer\GAL4Ras64B.PW, Scer\GAL4C23 or Scer\GAL4repo at 18[o]C suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of cnkKK109209 under the control of either Scer\GAL4Ras64B.PW or Scer\GAL4C23 suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of CCKLR-17D1KK108482 under the control of either Scer\GAL4Ras64B.PW or Scer\GAL4C23 suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of Scer\GAL4repo has no significant effect.
Expression of CCKLR-17D3GD3431 under the control of either Scer\GAL4Ras64B.PW, Scer\GAL4C23 or Scer\GAL4repo does not suppress the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of RetK805A.Scer\UAS under the control of Scer\GAL4Ret.PW does not suppress the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of Dap160KK102297 under the control of either Scer\GAL4Ras64B.PW, Scer\GAL4C23 or Scer\GAL4nSyb.PS suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of Rab9KK109041 under the control of either Scer\GAL4Ras64B.PW or Scer\GAL4C23 suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of Rab9S26N.Scer\UAS.P\T.T:Avic\GFP-YFP under the control of either Scer\GAL4Act5C.PU, Scer\GAL4nSyb.PS or Scer\GAL4C23 suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Expression of NAAT1KK112890 under the control of either Scer\GAL4Ras64B.PW (in the presence of Dcr-2Scer\UAS.cDa to enhance RNAi), Scer\GAL4C23 or Scer\GAL4nSyb.PS suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of Scer\GAL4repo has no significant effect.
Expression of HERC2KK100181 under the control of Scer\GAL4Ras64B.PW suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of either Scer\GAL4C23 or Scer\GAL4repo has no significant effect.
Expression of Hs3st-BKK108793 under the control of either Scer\GAL4Ras64B.PW or Scer\GAL4C23 suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of Scer\GAL4repo has no significant effect.
The increase in mean number of boutons per neuromuscular junction which is seen in Nf1E2 third instar larvae is dominantly suppressed by Alk9, jebweli, cnkXE-385, and Df(1)Exel9051.
FakN30/FakKG00304 ; Nf1E2/+ larvae show an increase in bouton number per muscle area at the neuromuscular junction compared to wild type.
One copy of Alk1 partially suppresses the small pupae phenotype seen in Nf1E2 homozygotes by increasing cell size. The Nf1E2 olfactory learning phenotype is also partially rescued.
One copy of Alk9 partially suppresses the small pupae phenotype seen in Nf1E2 homozygotes by increasing cell size. The Nf1E2 olfactory learning phenotype is also partially rescued.
Expression of AlkScer\UAS.cLa under the control of Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4386Y in a Nf1E2 mutant background results in larval lethality. Larval lethality is also seen when AlkScer\UAS.cLa is expressed under the control of Scer\GAL4elav-C155 in a Nf1E2/+ background.
Expression of jebScer\UAS.cVa under the control of Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4386Y in a Nf1E2 mutant background results in larval lethality. In a Nf1E2/+ background pupae are able to develop and the small size phenotype is partially suppressed.
Expression of Alkact.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4386Y in a Nf1E2 mutant background results in larval lethality. Larval lethality is also seen when AlkScer\UAS.cLa is expressed under the control of Scer\GAL4elav-C155 in a Nf1E2/+ background.
Expression of AlkEC.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav-C155 significantly suppresses the small pupae phenotype seen in Nf1E2 homozygotes. The pupae seen are close to the size of controls. Rescue is also seen when AlkEC.Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4Ras64B.PW or Scer\GAL4386Y but to a lesser extent.
Expression of AlkGD42 under the control of Scer\GAL4elav-C155 rescues the small pupae phenotype seen in Nf1E2 homozygotes. The pupae seen are close to the size of controls. Rescue is also seen when AlkEC.Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4Ras64B.PW but the rescue is not as efficient. The increase in size is due to increased cell size rather than increased cell number. Expression of AlkGD42 under the control of Scer\GAL4386Y also partially rescues the phenotype in Nf1E2.
Expression of AlkEC.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4ey-OK107 does not suppress the small pupae phenotype seen in Nf1E2 mutants.
Expression of AlkGD42 under the control of Scer\GAL4ey-OK107 does not suppress the small pupae phenotype seen in Nf1E2 mutants.
Expression of AlkEC.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Ccap.PP does not suppress the small pupae phenotype seen in Nf1E2 mutants.
Expression of AlkGD42 under the control of Scer\GAL4Ccap.PP does not suppress the small pupae phenotype seen in Nf1E2 mutants.
Expression of AlkEC.Scer\UAS.T:Hsap\MYC under the control of either the Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4Alk.38 driver, and restricted to the adult stages using Scer\GAL80ts.αTub84B, rescues the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of AlkEC.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4c747, and restricted to the adult stages using Scer\GAL80ts.αTub84B, fails to rescue the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of AlkGD42 under the control of either the Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4Alk.38 driver, and restricted to the adult stages using Scer\GAL80ts.αTub84B, rescues the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of AlkGD42 under the control of Scer\GAL4c747, and restricted to the adult stages using Scer\GAL80ts.αTub84B, fails to rescue the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of Mmus\Pkacaact.2xScer\UAS under the control of either Scer\GAL4Aug21 or Scer\GAL4Akh.PW suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of either Scer\GAL4Feb36, Scer\GAL4elav.PU, Scer\GAL4Ras64B.PW or Scer\GAL4C23 does not significantly suppress the phenotype.
Expression of Mmus\Pkacaact.3xScer\UAS under the control of either Scer\GAL4Feb36, Scer\GAL4Aug21 or Scer\GAL4Akh.PW suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of either Scer\GAL4elav.PU, Scer\GAL4Ras64B.PW or Scer\GAL4C23 does not significantly suppress the phenotype.
Expression of Mmus\Pkacaact.4xScer\UAS under the control of either Scer\GAL4Aug21 or Scer\GAL4Akh.PW suppresses the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of either Scer\GAL4elav.PU or Scer\GAL4C23 does not significantly suppress the phenotype.
Expression of Mmus\PkacamC.Scer\UAS under the control of Scer\GAL4Akh.PW suppresses the reduced pupal length phenotype seen in Nf1E2 animals.
Nf1E2 is rescued by Scer\GAL4Act5C.PU/Nf1UAS.cWa
Nf1E2 is rescued by Scer\GAL4elav.PU/Nf1UAS.cWa
Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4Ras64B.PW
Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4C23
Nf1E2 is rescued by Nf1K1481A.hs
Nf1E2 is rescued by Nf1K1481A.hs
Nf1E2 is rescued by Scer\GAL4elav.PU/Nf1UAS.CFP
Nf1E2 is rescued by Scer\GAL4elav.PU/Nf1UAS.CFP
Nf1E1/Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4Alk.38
Nf1E1/Nf1E2 is rescued by Scer\GAL4elav-C155/Nf1UAS.cWa/Scer\GAL80ts.αTub84B
Nf1E1/Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4Ras64B.PW/Scer\GAL80ts.αTub84B
Nf1E1/Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4Alk.38/Scer\GAL80ts.αTub84B
Nf1E2 is rescued by Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI/Nf1UAS.cWa
Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4C23
Nf1E2 is rescued by Scer\GAL4elav-C155/Nf1UAS.cWa
Nf1E2 is rescued by Nf1UAS.cWa/Scer\GAL4Ras64B.PW
Nf1E2 is rescued by Scer\GAL4Ras85D.PW/Nf1UAS.cWa
Nf1E2 is rescued by Nf1Δ492-1094.hs
Nf1E2 is rescued by Nf1Δ1611-1769.hs
Nf1E2 is rescued by Nf1Δ1770-2265.hs
Nf1E2 is rescued by Nf1K1481A.hs
Nf1E2 is rescued by Nf1GRD.UAS.Tag:HA/Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI
Nf1E2 is rescued by Nf1GRD.UAS.Tag:HA/Scer\GAL4Ras64B.PW
Nf1E2 is rescued by Nf1GRD.UAS.Tag:HA/Scer\GAL4Ras85D.PW
Nf1E2 is partially rescued by Nf1R1320P.hs
Nf1E2 is partially rescued by Nf1R1320P.hs
Nf1E2 is partially rescued by Nf1Δ1219-1580.hs
Nf1E2 is partially rescued by Nf1Δ1219-1580.hs
Nf1E1/Nf1E2 is partially rescued by Scer\GAL4elav-C155/Nf1UAS.cWa
Nf1E2 is partially rescued by Nf1GRD.UAS.Tag:HA/Scer\GAL4C23
Nf1E2 is partially rescued by Nf1K1481A.GRD.UAS.Tag:HA/Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI
Nf1E2 is partially rescued by Nf1K1481A.GRD.UAS.Tag:HA/Scer\GAL4C23
Nf1E2 is not rescued by Nf1UAS.cWa/Scer\GAL4Ret.PW
Nf1E2 is not rescued by Scer\GAL4Feb36/Nf1UAS.cWa
Nf1E2 is not rescued by Scer\GAL4Aug21/Nf1UAS.cWa
Nf1E2 is not rescued by Scer\GAL4Akh.PW/Nf1UAS.cWa
Nf1E2 is not rescued by Scer\GAL4C57/Nf1UAS.CFP
Nf1E2 is not rescued by Scer\GAL4C57/Nf1UAS.CFP
Nf1E2 is not rescued by Scer\GAL4elav.PU/Nf1ΔA.UAS.CFP
Nf1E2 is not rescued by Scer\GAL4elav.PU/Nf1ΔA.UAS.CFP
Nf1E1/Nf1E2 is not rescued by Scer\GAL4c747/Nf1UAS.cWa/Scer\GAL80ts.αTub84B
Nf1E1/Nf1E2 is not rescued by Scer\GAL4Mef2.247/Nf1UAS.cWa/Scer\GAL80ts.αTub84B
Nf1E1/Nf1E2 is not rescued by Scer\GAL4ey-OK107/Nf1UAS.cWa/Scer\GAL80ts.αTub84B
Nf1E1/Nf1E2 is not rescued by Scer\GAL4en-e16E/Nf1UAS.cWa
Nf1E2 is not rescued by Nf1UAS.cWa/Scer\GAL4repo
Nf1E2 is not rescued by Nf1Δ1219-1580.hs
Nf1E2 is not rescued by Nf1R1320A.hs
Nf1E2 is not rescued by Nf1R1320P.hs
Nf1E2 is not rescued by Nf1Q1471R.hs
Nf1E2 is not rescued by Nf1GRD.UAS.Tag:HA/Scer\GAL4repo
Nf1E2 is not rescued by Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI/Nf1R1320A.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Nf1R1320A.GRD.UAS.Tag:HA/Scer\GAL4C23
Nf1E2 is not rescued by Scer\GAL4repo/Nf1R1320A.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI/Nf1R1320P.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Scer\GAL4C23/Nf1R1320P.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Scer\GAL4repo/Nf1R1320P.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Scer\GAL4Ras64B.PW/Nf1R1320P.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Scer\GAL4Ras85D.PW/Nf1R1320P.GRD.UAS.Tag:HA
Nf1E2 is not rescued by Nf1K1468T.GRD.UAS.Tag:HA/Scer\GAL4Act5C.PI/Scer\GAL4Act5C.PI
Nf1E2 is not rescued by Nf1K1468T.GRD.UAS.Tag:HA/Scer\GAL4C23
Nf1E2 is not rescued by Nf1K1468T.GRD.UAS.Tag:HA/Scer\GAL4repo
Nf1E2 is not rescued by Nf1K1481A.GRD.UAS.Tag:HA/Scer\GAL4repo
Expression of Nf1Scer\UAS.cWa under the control of either Scer\GAL4Act5C.PU, Scer\GAL4elav.PU, Scer\GAL4Ras64B.PW or Scer\GAL4C23 rescues the reduced pupal length phenotype seen in Nf1E2 animals, while expression under the control of either Scer\GAL4Ret.PW, Scer\GAL4Feb36, Scer\GAL4Aug21 or Scer\GAL4Akh.PW does not rescue.
Expression of Nf1Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4C57 fails to rescue the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae.
Expression of Nf1Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4elav.PU rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The increase in EJP amplitude is also largely rescued.
Expression of Nf1ΔA.Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4elav.PU fails to rescue the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae.
Nf1hs.PT rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The reduced body size of Nf1E2/Nf1E2 pupae is also rescued.
Nf1K1481A.hs rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The reduced body size of Nf1E2/Nf1E2 pupae is also rescued.
Nf1R1320P.hs rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The reduced body size of Nf1E2/Nf1E2 pupae is not rescued.
Nf1Δ1219-1580.hs rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The reduced body size of Nf1E2/Nf1E2 pupae is not rescued.
Expression of Nf1Scer\UAS.cWa under the control of Scer\GAL4Alk.38 rescues the small pupae phenotype seen in Nf1E2/Nf1E1 mutants.
Expression of Nf1Scer\UAS.cWa under the control of the mushroom body drivers Scer\GAL4c747, Scer\GAL4Mef2.247 or Scer\GAL4ey-OK107, and restricted to the adult stages using Scer\GAL80ts.αTub84B, fails to rescue the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of Nf1Scer\UAS.cWa under the control of the mushroom body drivers Scer\GAL4elav-C155, Scer\GAL4Ras64B.PW or Scer\GAL4Alk.38, and restricted to the adult stages using Scer\GAL80ts.αTub84B, fails to rescue the olfactory learning defects seen in Nf1E2/Nf1E1 mutants.
Expression of Nf1[Scer\UAS.cWa] under the control of the pan-neuronal driver Scer\GAL4elav-C155, as well as Scer\GAL80Mef2.PT to prevent expression in the mushroom bodies, rescues the olfactory learning defects seen in Nf1E2/Nf1E1 animals. Significant rescue is also seen with the Scer\GAL4Ras64B.PW and Scer\GAL4Alk.38 drivers.