twinGS8115/twinGS12209 larvae show a significant increase in the number of type 1b boutons at the muscle 6/7 neuromuscular junction compared to controls.
Embryos derived from twinGS12209/Df(3R)Exel6198 females mated to wild-type males show 66% lethality.
15% of embryos derived from twinGS12209/Df(3R)crb-F89-4 females that develop a cuticle have head defects, including complete loss of head structures.
Embryos derived from a cross of homozygous males and females show 94% lethality.
Embryos derived from twinGS12209/twinGS12209 females mated to wild-type males show 53% lethality.
Homozygous females show a number of ovarian defects; 60.5% of egg chambers are wild-type, but 4% have less than 15 nurse cells, 17.5% have more than 15 nurse cells, 14% show degeneration and 4% have other defects.
twinGS12209/Df(3R)crb-F89-4 females show a number of ovarian defects; 37% of egg chambers are wild-type, but 7.5% have less than 15 nurse cells, 32% have more than 15 nurse cells, 17.5% show degeneration and 6% have other defects. Eggs chambers containing oocytes with five ring canals are seen, indicating that the cyst has undergone an extra round of division.