100% of germaria lack germline stem cells (GSCs) in the ovaries of 7 day old twinGS8115/Df(3R)Exel6198 females.
Homozygous clonal GSCs are lost more rapidly from the germaria than control germline clones. Division in the mutant GSCs s slower than in wild type.
twinGS8115/twinGS12209 larvae show a significant increase in the number of type 1b boutons at the muscle 6/7 neuromuscular junction compared to controls.
Embryos derived from twinGS8115/twinGS8115 females mated to wild-type males show 78% lethality.
No eggs are produced from a cross of twinGS8115/Df(3R)Exel6198 females mated to wild-type males.
Homozygous females show a number of ovarian defects; 6% of egg chambers are wild-type, but 34% have less than 15 nurse cells, 36% have more than 15 nurse cells and 24% show degeneration.
twinGS8115/Df(3R)crb-F89-4 females show a number of ovarian defects; 14% of egg chambers are wild-type, but 20% have less than 15 nurse cells, 20% have more than 15 nurse cells, 43.5% show degeneration and 2.5% have other defects.