|Feature type||allele||Associated gene||Dmel\MP1|
|Mutagen||in vitro construct - regulatory fusion, in vitro construct - RNAi|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Carried in construct|
|Phenotype Manifest In|
Cuticle melanisation induced by B.bassiana is partially suppressed by expression of MP1[dsRNA.Scer\UAS.WIZ] under the control of Scer\GAL4[Act].
Approximately 50% of animals carrying MP1dsRNA.Scer\UAS.WIZ and Scer\GAL4Act die at the late pupal stage or during eclosion. Adults expressing MP1dsRNA.Scer\UAS.WIZ under the control of Scer\GAL4Act do not show melanisation around a wound site a few hours after infection by piercing with a tungsten needle harboring E.coli and M.luteus, in contrast to control flies which show significant melanisation around the wound site. Adult flies expressing MP1dsRNA.Scer\UAS.WIZ under the control of Scer\GAL4da.G32 show a similar survival rate to control flies after bacterial (E.carotovora, E.faecalis) and fungal (B.bassiana) infection.
MP1dsRNA.Scer\UAS.WIZ, Scer\GAL4Act.PU is a suppressor of lethal | larval stage phenotype of Scer\GAL4Act.PU, Spn77BadsRNA.WIZ.Scer\UAS
MP1dsRNA.Scer\UAS.WIZ, Scer\GAL4Act.PU is a suppressor of melanotic mass phenotype phenotype of Scer\GAL4Act.PU, Sp7Scer\UAS.P\T.T:SS-ea
|Phenotype Manifest In|
MP1dsRNA.Scer\UAS.WIZ, Scer\GAL4Act.PU is a suppressor of tracheal system phenotype of Scer\GAL4Act.PU, Spn77BadsRNA.WIZ.Scer\UAS
The lethality and melanisation of the adult tracheal system caused by expression of Spn77Ba[dsRNA.WIZ.Scer\UAS] under the control of Scer\GAL4[btl.PS] is suppressed by co-expression of MP1[dsRNA.Scer\UAS.WIZ].
Co-expression of MP1dsRNA.Scer\UAS.WIZ results in a further decrease in the survival rate of flies expressing DifdsRNA.IR.Scer\UAS under the control of Scer\GAL4da.G32 after fungal (C.albicans) infection. Co-expression of MP1dsRNA.Scer\UAS.WIZ results in a moderate further decrease in the survival rate of flies expressing BG4dsRNA.Scer\UAS under the control of Scer\GAL4da.G32 after bacterial (E.carotovora) infection.
|Complementation & Rescue Data|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 1 )|
|Secondary FlyBase IDs|
|References ( 2 )|