FB2025_02 , released April 17, 2025
Allele: Dmel\aosP372S.UAS
Open Close
General Information
Symbol
Dmel\aosP372S.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0197376
Feature type
allele
Associated gene
Dmel\aos
Associated Insertion(s)
Carried in Construct
P{UAS-aos.P372S}
Key Links
Transgenic product class
missense_variant
(Alvarado et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Alvarado et al., 2006)
Mutagen
ethyl methanesulfonate
(Alvarado et al., 2006)
Progenitor genotype
aosUAS.cAa
(Alvarado et al., 2006)
Carried in construct
P{UAS-aos.P372S}
Cytology
Description

Amino acid replacement: P372S.

(Alvarado et al., 2006)

Nucleotide substitution: C1114T.

(Alvarado et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
aos
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing argosP372S.Scer\UAS under the control of Scer\GAL4GMR.PF have a moderate rough eye phenotype.

      4% of flies expressing argosP372S.Scer\UAS under the control of Scer\GAL4Bx-MS1096 have a gap in the L4 wing vein.

      (Alvarado et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      aosP372S.UAS/Scer\GAL4hs.2sev partially rescues aosΔ7/Df(3L)Exel6129

      (Alvarado et al., 2006)
      Comments

      Expression of argosP372S.Scer\UAS under the control of Scer\GAL4hs.2sev results in significant (but not complete) rescue of the argosΔ7/Df(3L)Exel6129 eye phenotype.

      (Alvarado et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation within the P{UAS-argos.A} transgene that suppresses the rough eye phenotype caused by expression of argosScer\UAS.cAa under the control of Scer\GAL4GMR.PF.

      (Alvarado et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      aosP372S.Scer\UAS
      aosP372S.UAS
      argosP372S.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)