FlyBase Allele Report: Scer\GAL4[Lsp2.3.1]

General Information

Symbol

Scer\GAL4^Lsp2.3.1

Species

S. cerevisiae

Name

FlyBase ID

FBal0198120

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{3.1Lsp2-Gal4}

Also Known As

3.1Lsp2-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Lazareva et al., 2007)

Progenitor genotype

Carried in construct

P{3.1Lsp2-Gal4}

Cytology

Description

A 3.1kb promoter fragment from Lsp2 is cloned upstream of sequence encoding a GAL4 driver.

(Lazareva et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

Lsp2

Lsp2_3.1Lsp2-Gal4

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval fat body

(Lazareva et al., 2007)

adult stage

adult fat body

(Lazareva et al., 2007)

Additional Information

Statement

Reference

Marker for

Reflects expression of

Lsp2

(Bloomington Drosophila Stock Center, 2017, Lazareva et al., 2007)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal feeding behavior | adult stage, with fit^UAS.Tag:HA

(Sun et al., 2017)

abnormal size | adult stage, with Hex-C^GD12378

(Matsuoka et al., 2017)

abnormal size | adult stage, with Pepck1^GD9451

(Matsuoka et al., 2017)

abnormal size | adult stage, with Pepck1^GD16827

(Matsuoka et al., 2017)

abnormal starvation stress response, with Lpin^GD14004

(Ugrankar et al., 2011)

decreased cell death | adult stage | female, with apolpp^HMS00265

(Matsuoka et al., 2017)

decreased fecundity | female, with apolpp^HMS00265

(Matsuoka et al., 2017)

decreased fecundity | female, with crc^KK111018

(Vasudevan et al., 2022)

decreased occurrence of cell division | adult stage | female, with AcCoAS^HMS02314

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with Acly^GD3552

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with apolpp^GD3156

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with apolpp^HM05157

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with apolpp^HMS00265

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with CG3961^KK102693

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with Hex-C^GD12378

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with Pepck1^GD9451

(Matsuoka et al., 2017)

increased cell death | adult stage | female, with Pepck1^GD16827

(Matsuoka et al., 2017)

increased cell death | oogenesis, with crc^KK111018

(Grmai et al., 2024)

increased cell death | oogenesis, with Gcn2^KK103566

(Grmai et al., 2024)

increased cell death | oogenesis, with PEK^KK100348

(Grmai et al., 2024)

increased cell death | oogenesis, with Yp1^HMC06320

(Grmai et al., 2024)

increased size | adult stage, with bmm^JF01946

(Grmai et al., 2024)

increased size | adult stage, with crc^KK111018

(Grmai et al., 2024)

visible | maternal effect, with crc^KK111018

(Vasudevan et al., 2022)

Phenotype Manifest In

adult fat body, with bmm^JF01946

(Grmai et al., 2024)

adult fat body, with crc^KK111018

(Grmai et al., 2024)

dorsal appendage | maternal effect, with crc^KK111018

(Vasudevan et al., 2022)

egg chamber, with apolpp^GD3156

(Matsuoka et al., 2017)

egg chamber, with apolpp^HM05157

(Matsuoka et al., 2017)

egg chamber, with apolpp^HMS00265

(Matsuoka et al., 2017)

egg chamber, with Yp1^HMC06320

(Grmai et al., 2024)

egg chamber | decreased number, with crc^KK111018

(Grmai et al., 2024)

egg chamber | decreased number, with Gcn2^KK103566

(Grmai et al., 2024)

egg chamber | decreased number, with PEK^KK100348

(Grmai et al., 2024)

female germline stem cell, with AcCoAS^HMS02314

(Matsuoka et al., 2017)

female germline stem cell, with apolpp^GD3156

(Matsuoka et al., 2017)

female germline stem cell, with apolpp^HM05157

(Matsuoka et al., 2017)

female germline stem cell, with apolpp^HMS00265

(Matsuoka et al., 2017)

female germline stem cell, with CG3961^GD2713

(Matsuoka et al., 2017)

female germline stem cell, with CG3961^KK102693

(Matsuoka et al., 2017)

female germline stem cell, with eas^GD10683

(Matsuoka et al., 2017)

female germline stem cell, with eas^KK102681

(Matsuoka et al., 2017)

female germline stem cell, with Fer1HCH^GD4853

(Matsuoka et al., 2017)

female germline stem cell, with Fer1HCH^GD16271

(Matsuoka et al., 2017)

female germline stem cell, with Pss^GD2753

(Matsuoka et al., 2017)

germarium, with apolpp^HMS00265

(Matsuoka et al., 2017)

germarium, with Hex-C^GD12378

(Matsuoka et al., 2017)

germarium, with Pepck1^GD9451

(Matsuoka et al., 2017)

germarium, with Pepck1^GD16827

(Matsuoka et al., 2017)

lipid droplet | adult stage, with bmm^JF01946

(Grmai et al., 2024)

lipid droplet | adult stage, with crc^KK111018

(Grmai et al., 2024)

oocyte, with crc^KK111018

(Grmai et al., 2024)

oocyte, with Gcn2^KK103566

(Grmai et al., 2024)

oocyte, with PEK^KK100348

(Grmai et al., 2024)

oocyte | decreased number, with CNMa^UAS.cKa

(Grmai et al., 2024)

oocyte | increased number, with CNMa^KK110796

(Grmai et al., 2024)

oocyte | increased number, with ETH^JF02141

(Grmai et al., 2024)

oocyte | increased number, with sNPF^JF01906

(Grmai et al., 2024)

oocyte | increased number, with Tk^JF01818

(Grmai et al., 2024)

stage S14 oocyte | increased number, with Ctet\tetX^TNT-LC.UAS

(Grmai et al., 2024)

stage S14 oocyte | increased number, with Gcn2^KK103566

(Grmai et al., 2024)

stage S14 oocyte | increased number, with PEK^KK100348

(Grmai et al., 2024)

yolk granule | decreased number, with crc^KK111018

(Grmai et al., 2024)

yolk granule | decreased number, with Gcn2^KK103566

(Grmai et al., 2024)

yolk granule | decreased number, with PEK^KK100348

(Grmai et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Lsp2.3.1, crc^KK111018 has increased cell death | oogenesis phenotype, non-enhanceable by mTor^UAS.Tag:MYC/Scer\GAL4^Lsp2.3.1

(Grmai et al., 2024)

Suppressed by

Statement

Reference

Scer\GAL4^Lsp2.3.1, crc^KK111018 has increased cell death | oogenesis phenotype, suppressible by Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1, crc^KK111018 has increased size | adult stage phenotype, suppressible by Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa

(Grmai et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^Lsp2.3.1, crc^KK111018 has increased cell death | oogenesis phenotype, non-suppressible by mTor^UAS.Tag:MYC/Scer\GAL4^Lsp2.3.1

(Grmai et al., 2024)

NOT Enhancer of

Statement

Reference

mTor^UAS.Tag:MYC/Scer\GAL4^Lsp2.3.1 is a non-enhancer of increased cell death | oogenesis phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa is a suppressor of increased cell death | oogenesis phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa is a suppressor of increased size | adult stage phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

NOT Suppressor of

Statement

Reference

mTor^UAS.Tag:MYC/Scer\GAL4^Lsp2.3.1 is a non-suppressor of increased cell death | oogenesis phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^Lsp2.3.1, crc^KK111018 has adult fat body phenotype, suppressible by Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1, crc^KK111018 has egg chamber | decreased number phenotype, suppressible by Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1, crc^KK111018 has lipid droplet | adult stage phenotype, suppressible by Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa

(Grmai et al., 2024)

Suppressor of

Statement

Reference

Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa is a suppressor of adult fat body phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa is a suppressor of egg chamber | decreased number phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Scer\GAL4^Lsp2.3.1/bmm^UAS.cGa is a suppressor of lipid droplet | adult stage phenotype of Scer\GAL4^Lsp2.3.1, crc^KK111018

(Grmai et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

crc^UAS.cKa/Scer\GAL4^Lsp2.3.1 rescues crc^{MI02300-GFSTF.1}

(Grmai et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (4)

Bloomington

84285

w^*; P{3.1Lsp2-Gal4}2; P{UAS-CC3Ai}3

84306

w^*; P{3.1Lsp2-Gal4}2; P{UAS-GC3Ai}3

84327

w^*; P{3.1Lsp2-Gal4}2; P{UAS-VC3Ai}3

98128

w^*; P{3.1Lsp2-Gal4}3/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Lsp2.3.1

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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