FB2025_01 , released February 20, 2025
Allele: Dmel\trp47
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General Information
Symbol
Dmel\trp47
Species
D. melanogaster
Name
FlyBase ID
FBal0198163
Feature type
allele
Associated gene
Dmel\trp
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Montell, 2008.2.18, Wang et al., 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: T674A.

(Wang et al., 2005)

Amino acid replacement: W684R.

(Wang et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:29,917,104..29,917,104 [-]
Nucleotide change:

A29917104G

Amino acid change:

T674A | trp-PA

Reported amino acid change:

T674A

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Wang et al., 2005)
point_mutation
3R:29,917,074..29,917,074 [-]
Nucleotide change:

T29917074M

Amino acid change:

W684R | trp-PA

Reported amino acid change:

W684R

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Wang et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant third instar larvae show the same preference for 17.5[o]C over 14[o]C in a two-way choice test as do wild-type controls.

      (Kwon et al., 2010)

      Mutant flies have electroretinogram defects.

      (Wang et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      trp9

      (Wang et al., 2005)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: A mutation on the 3rd chromosome that has electroretinogram defects.

      (Wang et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      trp47
      (Kwon et al., 2010, Montell, 2008.2.18, Wang et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)