FB2025_01 , released February 20, 2025
Allele: Dmel\BsgGD15718
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General Information
Symbol
Dmel\BsgGD15718
Species
D. melanogaster
Name
FlyBase ID
FBal0198845
Feature type
allele
Associated gene
Dmel\Bsg
Associated Insertion(s)
Carried in Construct
P{GD15718}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
in vitro construct
(Dickson et al., 2007.7.18)
Progenitor genotype
Carried in construct
P{GD15718}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD15718
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of BsgGD15718 under the control of Scer\GAL4Stat92E-0092-G4 (in combination with tub-Gal80[ts] to restrict expression to the adult stage) leads to an increase in the presynaptic bouton number and disruptions in the actin cytoskeleton of the STAT-expressing pars intercerebralis neurons in the adult brain.

      (Brent and Rajan, 2020)

      Expressing BsgGD15718 under the control of Scer\GAL4fkh.PH leads to a significant proportion of individuals with some persisting salivary gland tissue 24h after puparium formation, i.e. 8hr after the time when this tissue is usually cleared in control individuals.

      (Velentzas et al., 2018)

      Adults expressing BsgGD15718 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

      (Neely et al., 2010)

      Expression under the control of Scer\GAL4Mef2.PR results in early pupal lethality.

      Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.

      Expression under the control of Scer\GAL4Mef2.PR results in sarcomeres with irregular aggregates of Z-lines in the larval body wall muscles.

      (Schnorrer et al., 2010)

      Expression under the control of Scer\GAL4pnr-MD237 results in a colour difference between the central Scer\GAL4pnr-MD237 expression domain of the notum and the surrounding lateral region in 100% or 90-100% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.

      (Mummery-Widmer et al., 2009)
      External Data
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The accumulation of lipid droplets in glial cells in the vicinity of adult photoreceptor neurons expressing ND-42ninaE.GD6220 is ameliorated by the expression of BsgGD15718 when driven by either Scer\GAL454C or Scer\GAL4elav.PLu.

      (Liu et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 1 )
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      BsgGD15718
      Name Synonyms
      Secondary FlyBase IDs
        References (12)