Allele Dmel\CG43921^GD15014

General Information
Symbol	Dmel\CG43921^GD15014	Species	D. melanogaster
Name		FlyBase ID	FBal0199296
Feature type	allele	Associated gene	Dmel\CG43921

Map ( GBrowse )
Allele class
Mutagen	in vitro construct - RNAi, in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Dickson et al., 2007.7.18) in vitro construct - RNAi (Dickson et al., 2007.7.18)
Mutations Mapped to the Genome

Type Location Additional Notes References RNAi reagent :1..316
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of an inverted repeat. (Dickson et al., 2007.7.18)
Carried in construct	P{GD15014} (Dickson et al., 2007.7.18, Mummery-Widmer et al., 2009, Weber et al., 2012)
Associated Sequence Features	dsRNA-GD15014
Cytology
Phenotypic Data
Phenotypic Class
	planar polarity defective, with Scer\GAL4^hs.2sev (Weber et al., 2012) viable, with Scer\GAL4^pnr-MD237 (Mummery-Widmer et al., 2009)
Phenotype Manifest In
	ommatidium, with Scer\GAL4^hs.2sev (Weber et al., 2012) wing hair \| supernumerary, with Scer\GAL4^en-e16E (Weber et al., 2012) wing vein, with Scer\GAL4^en-e16E (Weber et al., 2012)
Detailed Description
	Statement Reference Expression of CG43921[GD15014] using Scer\GAL4[hs.2sev] results in planar cell polarity (PCP)-abnormalities in ommatidia. Scer\GAL4[en-e16E]>CG43921[GD15014] induces multiple cellular hairs and vein defects in the wing. Flies expressing CG43921[GD15014] under the control of Scer\GAL4[ap-md544] display normal ommatidia and wing patterning. (Weber et al., 2012)
External Data
Linkouts	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 15014
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is an enhancer of planar polarity defective phenotype of Scer\GAL4^hs.2sev, pk^{sple.Scer\UAS} (Weber et al., 2012)
NOT Enhancer of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is a non-enhancer of planar polarity defective phenotype of Scer\GAL4^hs.2sev, dgo^Scer\UAS.cFa (Weber et al., 2012)
NOT Suppressor of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is a non-suppressor of planar polarity defective phenotype of Scer\GAL4^hs.2sev, dgo^Scer\UAS.cFa (Weber et al., 2012)
Phenotype Manifest In
Enhancer of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, pk^{sple.Scer\UAS} (Weber et al., 2012)
NOT Enhancer of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is a non-enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, dgo^Scer\UAS.cFa (Weber et al., 2012)
NOT Suppressor of
Statement Reference CG43921^GD15014, Scer\GAL4^hs.2sev is a non-suppressor of ommatidium phenotype of Scer\GAL4^hs.2sev, dgo^Scer\UAS.cFa (Weber et al., 2012)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 3 )
VDRC	v47795 w¹¹¹⁸; P{GD15014}v47795 v50598 w¹¹¹⁸; P{GD15014}v50598 v47796 w¹¹¹⁸; P{GD15014}v47796/TM3
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts
	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 15014
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG11146^GD15014 CG42251^GD15014 CG43921^GD15014
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Weber et al., 2012, Genetics 191(1): 145--162 Novel regulators of planar cell polarity: a genetic analysis in Drosophila. [FBrf0218210]
Supplementary material	Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]

Allele Dmel\CG43921GD15014

Allele Dmel\CG43921^GD15014