UASt regulatory sequences drive expression of an inverted repeat.
Expression of one or two copies of Abca3GD3708 under the control of Scer\GAL4elav.PLu leads to an increase in the active zone number at neuromuscular junctions (of muscle 4 of the A3 and A4 segment) in third instar larvae and a reduction in larval olfactory learning abilities when compared to controls.
Expression of ABCAGD3708 under the control of either Scer\GAL4GR1 or Scer\GAL4nos.UTR.T:Hsim\VP16 does not induce any nurse cell clearance defect in mutant stage 14 egg chambers and like in wild-type all the germ-line derived nurse cells have undergone programmed cell death and been cleared by this stage.
Expression of ABCAGD3708 under the control of Scer\GAL4elav.PLu leads to a significant increase in average distance between male adults (from one or two copies of ABCAGD3708) or between female adults (only from two copies of ABCAGD3708), despite no significant changes in locomotor ability, as compared to controls. Reared under 12h:12h light:dark cycles, these adults present increases in morning activity peak, in evening peak activity (including an early onset of activity), and in midday siesta activity (which are more evident if expressing from two copies than from one copy of the transgene), as compared to controls; these adult males also exhibit an increase in night time sleep if expressing from one, but not from two, transgene copy, as compared to controls.
The neuromuscular junctions of third instar larvae expressing from one or two copies of ABCAGD3708 under the control of Scer\GAL4elav.PLu exhibit a significant increase in the number of satellite boutons, but exhibit no obvious changes in the number of mature boutons, or in either the number or length of branches, as compared to controls.
Adults expressing CG1718GD3708 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Abca3GD3708, Scer\GAL4elav.PLu has increased rate of movement | adult stage phenotype, enhanceable by hpoKC202
Abca3GD3708, Scer\GAL4elav.PLu has increased rate of movement | adult stage phenotype, non-enhanceable by hpoKS240
Abca3GD3708, Scer\GAL4elav.PLu has increased rate of movement | adult stage phenotype, non-enhanceable by rhoGD2243, Scer\GAL4elav.PLu
Abca3GD3708, Scer\GAL4elav.PLu has increased rate of movement | adult stage phenotype, non-suppressible by rhoGD2243, Scer\GAL4elav.PLu
Abca3GD3708, Scer\GAL4elav.PLu has increased rate of movement | adult stage phenotype, non-suppressible by hpoKS240
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | third instar larval stage | increased number phenotype, non-enhanceable by hpoKS240
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | third instar larval stage | increased number phenotype, non-enhanceable by ykiB5
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | third instar larval stage | increased number phenotype, non-enhanceable by enaHMS01953, Scer\GAL4elav.PLu
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | increased number | third instar larval stage phenotype, suppressible by hpoKC202
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | increased number | third instar larval stage phenotype, suppressible by wtsx1
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | increased number | third instar larval stage phenotype, non-suppressible by hpoKS240
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | increased number | third instar larval stage phenotype, non-suppressible by ykiB5
Abca3GD3708, Scer\GAL4elav.PLu has NMJ bouton | increased number | third instar larval stage phenotype, non-suppressible by enaHMS01953, Scer\GAL4elav.PLu