FlyBase Allele Report: Dmel\Ugt36E1[GD1766]

General Information

Symbol

Dmel\Ugt36E1^GD1766

Species

D. melanogaster

Name

FlyBase ID

FBal0201838

Feature type

allele

Associated gene

Dmel\Ugt36E1

Associated Insertion(s)

Carried in Construct

P{GD1766}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD1766}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD1766

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | virgin male, with Scer\GAL4^{neur-GAL4-A101}

(Fraichard et al., 2020)

abnormal courtship behavior | virgin male, with Scer\GAL4^Orco.PK

(Fraichard et al., 2020)

abnormal neurophysiology | adult stage | male, with Scer\GAL4^Orco.PK

(Fraichard et al., 2020)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Ugt36E1^GD1766 under the control of Scer\GAL4^{neur-GAL4-A101} leads to an increased sex discrimination in males under red light when compared to controls.

Expression of Ugt36E1^GD1766 under the control of Scer\GAL4^Gr66a.PD leads to no change in sex discrimination in males under red light when compared to controls.

Expression of Ugt36E1^GD1766 under the control of Scer\GAL4^Orco.PK leads to an increased sex discrimination in males under red light when compared to controls, and no difference of relative responses to male and female volatile compounds when compared to controls (which show a larger relative response to male than to female volatile compounds).

(Fraichard et al., 2020)

Adults expressing CG17322^GD1766 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

1766

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Knockdown of Ugt36E1 levels by expressing Ugt36E1^GD1766 under the control of Scer\GAL4^Orco.PK rescues the decreased sex discrimination phenotype of Ugt36E1^KG04070/Ugt36E1^KG04070 homozygous mutant males (the Ugt36E1^KG04070 mutation increases Ugt36E1 expression levels relative to controls).

(Fraichard et al., 2020)

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v6384

w¹¹¹⁸; P{GD1766}v6384

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts