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General Information
Symbol
Dmel\snRNP-U1-CGD11660
Species
D. melanogaster
Name
FlyBase ID
FBal0204688
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of snRNP-U1-CGD11660 under the control of Scer\GAL4ninaE.PU slightly, but significantly increases electroretinogram amplitude in 5 day old adults, compared to controls.

Expression under the control of Scer\GAL41407 results in an increase in the average size of neuroblasts in the larval brain compared to controls.

Expression under the control of Scer\GAL41407 may result in loss of neuroblasts in the larval brain (depending on the insertion line used).

Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.

Expression under the control of Scer\GAL41407 may result in mild defects in the shape of ganglion mother cells in the larval brain (depending on the insertion line used).

Expression under the control of Scer\GAL41407 results in mild defects in the shape of neuroblasts in the larval brain.

Adults expressing snRNP-U1-CGD11660 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Expression of snRNP-U1-CGD11660 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD11660} insertion line used.

Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies or late larval lethality.

Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.

Expression under the control of Scer\GAL4Mef2.PR results in sarcomeres with irregular aggregates of Z-lines in the larval body wall muscles.

Expression under the control of Scer\GAL4Mef2.PR results in grossly normal adult indirect flight muscles.

Expression under the control of Scer\GAL4Mef2.PR results in frayed myofibrils in the adult indirect flight muscles.

Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the adult indirect flight muscles.

Expression under the control of Scer\GAL4pnr-MD237 results in lethality or semi-lethality at the pupal stage, depending on the insertion line used.

Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 70-80% of the Scer\GAL4pnr-MD237-expressing area of the notum.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Enhancer of
NOT Enhancer of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 2 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Neuroblasts Screen Database (Knoblich Lab) - A database for RNAi phenotypes in larval neural stem cells
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
CG5454GD11660
snRNP-U1-CGD11660
snRNP-U1GD11660
snRNP-U1Cv22132
snRNP-U1Cv22133
Name Synonyms
Secondary FlyBase IDs
    References (8)