Allele Dmel\hppy^GD12129

General Information
Symbol	Dmel\hppy^GD12129	Species	D. melanogaster
Name		FlyBase ID	FBal0205328
Feature type	allele	Associated gene	Dmel\hppy

Map ( GBrowse )
Allele class
Mutagen	in vitro construct - RNAi, in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Dickson et al., 2007.7.18) in vitro construct - RNAi (Dickson et al., 2007.7.18)
Mutations Mapped to the Genome

Type Location Additional Notes References RNAi reagent :1..306
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of an inverted repeat. (Dickson et al., 2007.7.18)
Carried in construct	P{GD12129} (Dickson et al., 2007.7.18, Resnik-Docampo and de Celis, 2011, Mummery-Widmer et al., 2009)
Associated Sequence Features	dsRNA-GD12129
Cytology
Phenotypic Data
Phenotypic Class
	viable, with Scer\GAL4^pnr-MD237 (Mummery-Widmer et al., 2009)
Phenotype Manifest In

Detailed Description
	Statement Reference Co-expression of hppy[GD12129] suppresses the small wing phenotype of hppy[EP-704], Scer\GAL4[nub-AC-62] flies. Expression of hppy[GD12129] using Scer\GAL4[nub-AC-62] is not associated with any mutant phenotype in the adult wing. (Resnik-Docampo and de Celis, 2011)
External Data
Linkouts	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 12129
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference hppy^GD12129/Scer\GAL4^MD-638 is a suppressor of size defective phenotype of Scer\GAL4^MD-638, Tor^TED.Scer\UAS (Resnik-Docampo and de Celis, 2011) hppy^GD12129/Scer\GAL4^nub-AC-62 is a suppressor of size defective phenotype of Scer\GAL4^nub-AC-62, Tor^TED.Scer\UAS (Resnik-Docampo and de Celis, 2011)
Phenotype Manifest In
Suppressor of
Statement Reference hppy^GD12129/Scer\GAL4^MD-638 is a suppressor of wing phenotype of Scer\GAL4^MD-638, Tor^TED.Scer\UAS (Resnik-Docampo and de Celis, 2011) hppy^GD12129/Scer\GAL4^nub-AC-62 is a suppressor of wing phenotype of Scer\GAL4^nub-AC-62, Tor^TED.Scer\UAS (Resnik-Docampo and de Celis, 2011)
Additional Comments
Genetic Interactions
Statement Reference Co-expression of hppy[GD12129] significantly rescues the reduced wing size caused by expression of Tor[TED.Scer\UAS] using Scer\GAL4[nub-AC-62] or Scer\GAL4[MD-638]. (Resnik-Docampo and de Celis, 2011)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
VDRC	v35166 w¹¹¹⁸; P{GD12129}v35166
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts
	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 12129
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	CG7097^GD12129 hppy^GD12129
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Resnik-Docampo and de Celis, 2011, PLoS ONE 6(1): e14528 MAP4K3 Is a Component of the TORC1 Signalling Complex that Modulates Cell Growth and Viability in Drosophila melanogaster. [FBrf0212911]
Supplementary material	Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]

Allele Dmel\hppyGD12129

Allele Dmel\hppy^GD12129