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General Information
Symbol
Dmel\Ars2GD12300
Species
D. melanogaster
Name
FlyBase ID
FBal0205631
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression under the control of Scer\GAL41407 results in mild defects in the shape of neuroblasts in the larval brain.
Adults expressing Ars2GD12300 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies or late pupal lethality. Expression under the control of Scer\GAL4Mef2.PR results in grossly normal adult indirect flight muscles. Expression under the control of Scer\GAL4Mef2.PR results in frayed myofibrils in the adult indirect flight muscles. Expression under the control of Scer\GAL4Mef2.PR results in sarcomeres with broadened Z-lines in the adult indirect flight muscles.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used. Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 80-90% of the Scer\GAL4pnr-MD237-expressing area of the notum.
Adult flies expressing CG7843GD12300 under the control of Scer\GAL4hs.PB (induced using heat shock) succumb to infection with DCV earlier than control flies. The mutant flies show increased production of viral capsid proteins compared to controls. Adult flies expressing CG7843GD12300 under the control of Scer\GAL4hs.PB (induced using heat shock) show a significant increase in mortality after infection with VSV, in contrast to control flies which do not succumb to VSV infection.
External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 2 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Neuroblasts Screen Database (Knoblich Lab) - A database for RNAi phenotypes in larval neural stem cells
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ars2GD12300
CG7843GD12300
Name Synonyms
Secondary FlyBase IDs
    References (9)