Expression of Skp2^GD5142 under the control of either Scer\GAL4^en-e16E or Scer\GAL4^nub-AC-62 leads to a wing hair spacing phenotype. The space between wing hairs becomes larger, with irregular orientation and frequent clustering of wing hairs. Expression of Skp2^GD5142 under the control of Scer\GAL4^ey.PH results in a rough eye phenotype. Expression of Skp2^GD5142 (co-expressed with Dcr-2^Scer\UAS.cDa) under the control of Scer\GAL4^en-e16E at 29[o]C results in reduced wing disc cell density compared to controls. Wing disc clones expressing Skp2^GD5142 under the control of Scer\GAL4^Act5C.PP contain fewer cells than wild type, containing on average 26 cells compared to 143 in the controls. Flies expressing Skp2^GD5142 under the control of Scer\GAL4^vg.PU exhibit wing margin nicking. Expression of Skp2^GD5142 in the notum under the control of Scer\GAL4^pnr-MD237 results in dorsal closure defects and abnormal bristle patterning.

(Dui et al., 2013)

Expression of Skp2^GD5142 under the control of Scer\GAL4^ptc-559.1 results in a reduction in salivary gland size and a reduction in ploidy of the nuclei of the salivary gland cells in wandering third instar larvae. Expression of Skp2^GD5142 under the control of Scer\GAL4^en-e16E results in increased spacing of the wing hairs near the anterior/posterior compartment boundary.

(Ghorbani et al., 2011)

Adults expressing Skp2^GD5142 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression under the control of Scer\GAL4^pnr-MD237 results in loss of bristles on the notum in 10-20% of the Scer\GAL4^pnr-MD237 expression domain. Expression under the control of Scer\GAL4^pnr-MD237 results in bristle morphology defects on the notum in 40-50% of the Scer\GAL4^pnr-MD237 expression domain. Expression under the control of Scer\GAL4^pnr-MD237 results in the absence of 40-50% of the Scer\GAL4^pnr-MD237-expressing area of the notum.

(Mummery-Widmer et al., 2009)