under the control of Scer\GAL4P2.4.Pdf
leads to a significant increase in sleep duration during both day time and night time (ZT1-12 and ZT13-24, respectively), and leads to a significant decrease in sleep latency period as compared to controls. This expression also induces a significant increase in GABA-receptor-mediated current in adult arousal-promoting large ventral lateral neurons (lLNvs), as compared to controls.
Adults expressing Fbxl4GD5204
under the control of Scer\GAL4elav.PLu
(in the presence of Dcr-2Scer\UAS.cDa
to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.