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General Information
Symbol
Dmel\NrgGD82
Species
D. melanogaster
Name
FlyBase ID
FBal0207787
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Presynaptic expression of NrgGD82 under the control of Scer\GAL4elav-C155 results in synaptic retraction in third instar larval NMJs. The frequency of retractions is increased when NrgGD82 is co-expressed with Dcr-2Scer\UAS.cDa, or if two motor neuron drivers are used in combination (Scer\GAL4elav-C155 and Scer\GAL4VGlut-OK371).

Muscle-specific expression of NrgGD82 under the control of Scer\GAL4Mef2.PU (co-expressed with Dcr-2Scer\UAS.cDa) does not produce synaptic retraction in third instar larval NMJs.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Fas2Scer\UAS.cLa fails to suppress the synaptic retraction phenotype seen in the NMJs of third instar larvae when NrgGD82 is expressed under the control of Scer\GAL4elav-C155 and Scer\GAL4VGlut-OK371.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of NrgScer\UAS.180.cEa significantly rescues the synapse retraction phenotype seen when NrgGD82 is expressed under the control of Scer\GAL4elav-C155 and Scer\GAL4VGlut-OK371.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
NrgGD82
Name Synonyms
Secondary FlyBase IDs
    References (8)