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General Information
Symbol
Dmel\bowlGD1389
Species
D. melanogaster
Name
FlyBase ID
FBal0209172
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-BowlRNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of bowlGD1389 under the control of Scer\GAL4klu-G410 results in a reduction in the extent of the prescutum and eliminates lateral microchaetae in the ventral prescutum.

Adults expressing bowlGD1389 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Expression of bowlGD1389 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD1389} insertion line used.

Expression under the control of Scer\GAL4pnr-MD237 results in extra bristles on the notum in 0% or 10-20% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.

Expression under the control of Scer\GAL4pnr-MD237 results in planar polarity defects in the orientation of bristles of the notum in 20-30% of the Scer\GAL4pnr-MD237 expression domain.

Expression of bowlGD1389 under the control of Scer\GAL4pnr-MD237 leads to a mild thorax closure phenotype.

Expression of bowlGD1389 under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF leads to a mild rough eye phenotype.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of Dcr-2Scer\UAS.cDa with bowlGD1389, under the control of Scer\GAL4ey.PH and Scer\GAL4GMR.PF enhances the bowlGD1389 rough eye phenotype and results in lethality.

Coexpression of Dcr-2Scer\UAS.cDa with bowlGD1389, under the control of Scer\GAL4pnr-MD237, enhances the bowlGD1389 thorax closure phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
bowlGD1389
Name Synonyms
Secondary FlyBase IDs
    References (8)