Expression of cpxGD10482 under the control of Scer\GAL4C164 leads to increased frequency of mini excitatory junction potentials (~spontaneous releases) as well as synaptic overgrowth (increased number of boutons per muscle area) at third instar larval neuromuscular junctions.
Adults expressing cpxGD10482 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies or late pupal lethality.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in mild thorax closure defects.
Expression under the control of Scer\GAL4pnr-MD237 results in an enlarged notum.