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General Information
Symbol
Dmel\egrGD12658
Species
D. melanogaster
Name
FlyBase ID
FBal0209506
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of egrGD12658 under the control of either Scer\GAL4hh-Gal4 or Scer\GAL4Hml.Δ does not lead to any obvious phenotype in the wing disc, as compared to controls.

Adults expressing egrGD12658 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Flies co-expressing egrScer\UAS.cMa and egrGD12658 under the control of Scer\GAL4GMR.PF display normal eyes.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of egrGD12658 does not suppress the increase in circulating lamellocytes seen when ND75GD6309 is expressed under the control of Scer\GAL4Antp-10.

Expression of egrGD12658 under the control of Scer\GAL4tub.PU does not affect the reduction in l(2)gl4 mutant wing disc clone size compared with controls.

Xenogenetic Interactions
Statement
Reference

Co-expression of egrGD12658 partially suppresses the increased cell death in the brain, the climbing defects, and the shortened lifespan seen in Ecc15-infected flies expressing Hsap\APPAβ42.Scer\UAS.cBa under the control of Scer\GAL4elav-C155.

Complementation and Rescue Data
Comments

The dot-like malformed adult eye phenotype seen in flies expressing egrScer\UAS.cMa under the control of Scer\GAL4GMR.PFa can be fully restored by co-expression of egrGD12658 RNAi.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
egrGD12658
Name Synonyms
Secondary FlyBase IDs
    References (11)