UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing linGD1479 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of linGD1479 under the control of Scer\GAL4bab1-Pgal4-2 in the leg results in distal tarsal segment fusion with t1 and differentiated sex comb bristles.
Expression of linGD1479 under the control of Scer\GAL4bab1-Agal4-5 in the leg results in distal tarsal segment fusion with t1 and differentiated sex comb bristles.
Expression of linGD1479 under the control of Scer\GAL4rn-GAL4-DeltaS in the leg results in distal tarsal segment fusion with t1 and differentiated sex comb bristles.
Expression of linGD1479 under the control of Scer\GAL4Dll-md23 in the leg results in fusion of all the leg tarsal segments and the differentiation of sex comb bristles along the fused tarsus.
Expression of linGD1479 under the control of Scer\GAL4dac-p7d23 along the intermediate region of the leg disc results in a severe decrease in the size of true segments, and loss of true joints. Bristled-cuticle is replaced with naked cuticle, and numerous vesicles form under the basal surface of the epithelium within the leg shaft.
Expression of linGD1479 under the control of Scer\GAL4Dll-md23 in the antennae results in replacement of the AIII, the basal cylinder, and the arista with a poorly differentiated tubular structure.
Expression of linGD1479 under the control of Scer\GAL4bab1-Pgal4-2 or Scer\GAL4bab1-Agal4-5 in the antennae results in poor differentiation and expansion of the basal cylinder and aristal stalk.
Expression of linGD1479 under the control of Scer\GAL4rn-GAL4-DeltaS in the antenna distorts the morphology of AIII and results in poor differentiation of the basal cylinder.
Expression under the control of Scer\GAL4pnr-MD237 results in strong thorax closure defects.