Allele Dmel\mys^GD15002

General Information
Symbol	Dmel\mys^GD15002	Species	D. melanogaster
Name		FlyBase ID	FBal0210155
Feature type	allele	Associated gene	Dmel\mys

Map ( GBrowse )
Allele class
Mutagen	in vitro construct - RNAi, in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Dickson et al., 2007.7.18) in vitro construct - RNAi (Dickson et al., 2007.7.18)
Mutations Mapped to the Genome

Type Location Additional Notes References RNAi reagent :1..399
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of an inverted repeat. (Dickson et al., 2007.7.18)
Carried in construct	P{GD15002} (Dickson et al., 2007.7.18, Dietzl et al., 2007, Han et al., 2012, Lee et al., 2008, Mummery-Widmer et al., 2009)
Associated Sequence Features	dsRNA-GD15002
Cytology
Phenotypic Data
Phenotypic Class
	lethal, with Scer\GAL4^Mef2.PR (Dietzl et al., 2007) lethal, with Scer\GAL4^pnr-MD237 (Mummery-Widmer et al., 2009) lethal \| pupal stage, with Scer\GAL4^pnr-MD237 (Mummery-Widmer et al., 2009) neuroanatomy defective, with Scer\GAL4^21-7 (Han et al., 2012) partially lethal - majority die, with Scer\GAL4^elav.PLu (Dietzl et al., 2007)
Phenotype Manifest In
	dorsal multidendritic neuron ddaC, with Scer\GAL4^21-7 (Han et al., 2012) hub cell, with Scer\GAL4^C587 (Lee et al., 2008)
Detailed Description
	Statement Reference When mys[GD15002] is expressed in third instar larvae under the control of Scer\GAL4[21-7] (and co-expressed with Dcr-2[Scer\UAS.cDa]) 24.33% of the length of the ddaC dendrites at the dorsal midline are enclosed in the epidermis rather than attached to the ECM compared to only 5.69% in controls. (Han et al., 2012) Expression under the control of Scer\GAL4[pnr-MD237] results in lethality (either before or at the pupal stage), depending on the insertion line used. (Mummery-Widmer et al., 2009) Hub cells often fail to localise to the apical tip of the testis in males expressing mys[GD15002] under the control of Scer\GAL4[C587]. (Lee et al., 2008)
External Data
Linkouts	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 15002
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
VDRC	v29619 w¹¹¹⁸; P{GD15002}v29619 v29620 w¹¹¹⁸; P{GD15002}v29620/CyO
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts
	Bristle Screen Database - A database for RNAi phenotypes in bristle and notum development • 15002
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	mys^GD15002
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Han et al., 2012, Neuron 73(1): 64--78 Integrins Regulate Repulsion-Mediated Dendritic Patterning of Drosophila Sensory Neurons by Restricting Dendrites in a 2D Space. [FBrf0217239] Lee et al., 2008, Mech. Dev. 125(9-10): 768--776 Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization. [FBrf0207050] Dietzl et al., 2007, Nature 448(7150): 151--156 A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. [FBrf0200691]
Supplementary material	Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]

Allele Dmel\mysGD15002

Allele Dmel\mys^GD15002