FlyBase Allele Report: Dmel\rho[GD2243]

General Information

Symbol

Dmel\rho^GD2243

Species

D. melanogaster

Name

FlyBase ID

FBal0210461

Feature type

allele

Associated gene

Dmel\rho

Associated Insertion(s)

Carried in Construct

P{GD2243}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD2243}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD2243

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

Adults expressing rho^GD2243 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

rho^GD2243, Scer\GAL4^elav.PLu is a non-enhancer of increased rate of movement | adult stage phenotype of Abca3^GD3708, Scer\GAL4^elav.PLu

(Ueoka et al., 2020)

NOT Suppressor of

Statement

Reference

rho^GD2243, Scer\GAL4^elav.PLu is a non-suppressor of increased rate of movement | adult stage phenotype of Abca3^GD3708, Scer\GAL4^elav.PLu

(Ueoka et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PS/rho^GD2243 is a suppressor of eye phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

Scer\GAL4^GMR.PS/rho^GD2243 is a suppressor of ommatidium phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

Scer\GAL4^GMR.PS/rho^GD2243 is a suppressor of interommatidial bristle phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

Scer\GAL4^GMR.PS/rho^GD2243 is a suppressor of cone cell phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Knockdown of rho, through expression of rho^GD2243, suppresses the rough eye phenotype induced by expression of caz^KK107486.

(Shimamura et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

VDRC

v51952

w¹¹¹⁸; P{GD2243}v51952/TM3

v51953

w¹¹¹⁸; P{GD2243}v51953/TM3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

rho^GD2243

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

Open Close